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Galende,Sharize Betoni; Oliveira Neto,Oswaldo Custódio de; Santos,Leandro Freire dos; Peicher,Márcia Vardanega; Souza,Helenir Medri de; Bazotte,Roberto Barbosa. |
The activation of hepatic gluconeogenesis in male Wistar adult 6 h fasted rats during insulin-induced hypoglycemia (IIH) was previously demonstrated. In this study, the effects of intraperitoneal (ip) glucose (100 mg/kg) on the activation of liver gluconeogenesis during IIH was investigated. Thus, 6 h fasted rats that received ip regular insulin (1 U/kg) and 30 min later ip saline (Control group) or glucose (Experimental group) were compared. All the experiments were executed 60 min after insulin injection. The glycemia of Control and Experimental groups were not different (P > 0.05). To investigate gluconeogenesis, liver perfusion experiments were performed. The results demonstrated that excepting glycerol, livers from rats which received ip glucose... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hypoglycemia; Glycemia recovery; Hepatic metabolism; Gluconeogenesis; Ureagenesis. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000400008 |
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Moriel,Philipe; Cappellozza,Bruno Ieda; Ferraretto,Luiz Felipe; Aboin,Augusto Cossolino; Vieira,Fernanda Victor Rodrigues; Rodrigues,Ricardo de Oliveira; Cooke,Reinaldo Fernandes; Vasconcelos,José Luiz Moraes. |
Forty-five non-lactating, pregnant Holstein animals (18 heifers and 27 multiparous cows; BW = 561±114 kg; BCS = 2.9±0.3; days pregnant = 110±56 d) were stratified by initial BW and BCS, and randomly assigned to receive daily (as-fed basis) 0.50 kg of ground corn plus 0.22 kg of kaolin (CON), calcium salts of saturated fatty acids (SFA) or polyunsaturated fatty acids (PF) for 14 d. Blood samples were collected on days 0, 7 and 14, immediately prior to (0 h) and 3, 6, 9 and 12 h after feeding, to determine the serum concentrations of P4 and insulin. No treatment effects were detected for serum concentrations of P4 (5.52, 6.13 and 5.63±0.41 ng/mL for CON, SFA and PF, respectively). No treatment effects were detected for serum concentrations of insulin (11.5,... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hepatic metabolism; Linoleic; Linolenic; PUFA. |
Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982014000100004 |
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