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| HWANG,Jung Seok; LEE,Su Bi; CHOI,Mi-Jung; KIM,Jun Tae; SEO,Han Geuk. |
| Abstract We investigated the effects of a turmeric extract-loaded nanoemulsion (TENE) on lipid accumulation in 3T3-L1 adipocytes and in mice fed a high fat diet (HFD). The accumulation of intracellular lipid in 3T3-L1 adipocytes was significantly inhibited by TENE, according to Oil red O and Nile Red staining. This inhibitory effect of TENE on adipocyte differentiation was associated with lower expression levels of the adipocyte-specific genes, PPARγ, aP2, and C/EBPα. In HepG2 hepatocytes, TENE attenuated palmitate-induced intracellular accumulation of lipid and ROS. In mice fed a HFD, TENE significantly reduced the serum levels of total cholesterol, triglycerides, and LDL and increased HDL levels. These effects of TENE were accompanied by reductions in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Adipogenic differentiation; High fat diet; Nanoemulsion; Turmeric; 3T3-L1 preadipocytes. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612019000600439 |
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| Magalhães,Alan José Barbosa; Castoldi,Robson Chacon; Camargo,Regina Celi Trindade; Ozaki,Guilherme Akio Tamura; Costalonga,Regiane Rocha; Moreira,Rafael Junges; Seraphim,Patricia Monteiro; Camargo Filho,José Carlos Silva. |
| Studies indicate that increasing physical activity and decreasing levels of fat in the liver help to decrease the risk of morbidity from liver conditions. This study aimed to evaluate the effects of an eight week intermittent training program on the liver tissue of rats subjected to a hyperlipidic diet. The study consisted of 30 male Wistar rats, divided into the following groups: Sedentary Control (SC) Exercise Control (EC) (fed on standard feed and water) Sedentary Obese (SO) and Exercise Obese (EO) (fed on bacon, ham, sausage, biscuits, soda and standard feed), which performed intermittent training through electrically stimulated jumps, with three sets of 12 repetitions, three times per week for eight weeks. At the end of the training period, the... |
| Tipo: Journal article |
Palavras-chave: High fat diet; Exercise; Hepatocytes. |
| Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022016000100014 |
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