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Pharmacological activity of the hydroalcoholic extract from Hovenia dulcis thunberg fruit and the flavonoid dihydromyricetin during hypercholesterolemia induced in rats 60
Pinto,Juliana Tensol; Oliveira,Tânia Toledo de; Alvarenga,Luana Farah; Barbosa,Adriano Simões; Pizziolo,Virgínia Ramos; Costa,Marcelo Rocha da.
Cerebrovascular accidents and coronary artery disease are the leading causes of cardiovascular mortalities in Brazil and high levels of LDL cholesterol are one of the main risk factors. In this context, several plant extracts and natural substances have shown promise as cholesterol-lowering. The objective of this study was to evaluate the potential of the hydroalcoholic extract of the fruit of H. dulcisand of dihydromyricetin in cholesterol reduction in hypercholesterolemic rats. Forty-two Wistar male rats were distributed into seven groups of six animals that received diets supplemented with 1% cholesterol and 0.3% cholic acid, with the exception of the control group, which received conventional diets. Animals were treated with oral suspensions...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hovenia dulcis/pharmacognosy; Hovenia dulcis/hydroalcoholic extract/ cholesterol reduction; Hovenia dulcis/flavonoid dihydromyricetin/cholesterol reduction; Dihydromyricetin/cholesterol reduction; Hypercholesterolemia/experimental study; Medicinal plants.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400727
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