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	Provedor de dados International Journal of Morphology (1) Autor Arend,Andres (1) Aunapuu,Marina (1) Namm,Aimar (1) Palavra-chave BMP-2 (1) BMP-4 (1) Human embryo (1) Immunohistochemistry (1) Neural tube (1) Tipo do documento Journal article (1) Ano 2013 (1) País Chile (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Immunohistochemical Detection of BMP-2 and BMP-4 in the Developing Neural Tube and Spinal Cord of Human Embryos International Journal of Morphology Namm,Aimar; Arend,Andres; Aunapuu,Marina. The role of bone morphogenetic proteins (BMP-s) in the development of the nervous system has been widely studied on avian and rodent embryos. Human embryos have rarely been available for detection of BMP expression. In this study 39 human embryos of Carnegie stages (CS) 10-20 were investigated. The embryos were fixed in paraformaldehyde, embedded in paraffin and sectioned serially in transverse direction. BMP-2 and BMP-4 protein expression in the developing neural tube and the caudal spinal cord was determined by immunohistochemistry. Our data show that BMP-s tend to be more expressed in the neural tube in earlier stages; in particular, BMP-4 staining was found to be higher at CS10 compared to CS20. More detailed analysis was performed on embryos of... Tipo: Journal article Palavras-chave: Neural tube; Human embryo; BMP-2; BMP-4; Immunohistochemistry. Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200018 Registros recuperados: 1 Primeira ... 1 ... Última

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