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Registros recuperados: 3
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Prevalence of human papillomavirus infection in the genital tract determined by hybrid capture assay BJID
Carestiato,Fernanda N.; Silva,Katia C; Dimetz,Trude; Oliveira,Ledy H. S.; Cavalcanti,Silvia M. B..
Human Papillomavirus (HPV) infection is the most prevalent sexually-transmitted virus worldwide. It is known to be the etiological agent of cervical cancer and cervical intraepithelial neoplasia (CIN). Consequently, there is strong motivation to evaluate HPV testing in cervical cancer screening. Recently developed, the second generation of the hybrid capture test (HCA II) is a non-radioactive, relatively rapid, hybridization assay, designed to detect 18 HPV types divided into high and low-risk groups. We evaluated 7,314 patients (5,833 women and 1,481 men) for HPV infection by HCA II. Among them, 3,008 (41.1%) presented HPV infection: 430 (14.2%) had HPV DNA of low risk for cancer, 1,631 (54.2%) had high risk HPV types and 947 (31.5%) had both types. The...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HPV; SIL; Cancer; Hybrid capture.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000500006
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Diagnosis of human papillomatosis by polymerase chain reaction in cases of divergence between results of hybrid capture and papanicolaou cytology BJID
Novaes,Luiz Carlos Garcez; Novaes,Maria Rita Carvalho Garbi; Simões-Barbosa,Augusto.
As various types of human papillomavirus (HPV) are involved in the pathogenesis of cervical cancer, correct diagnosis is of fundamental importance for screening programs. We evaluated the divergence of results between Papanicolaou cytology and hybrid capture by PCR detection of HPV DNA . A transversal study was conducted on 70 women attending private gynecological clinics in Brasilia, Brazil. PCRs were conducted with specific primers for general and high-risk HPV DNA. Based on the PCR results, hybrid capture was a superior diagnostic technique. When Papanicolaou was compared with the molecular biology methods, it was found that a positive Papanicolaou result does not necessarily indicate the presence of HPV. The agreement between PCR and hybrid capture...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HPV; Diagnosis; Hybrid capture; PCR.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000300003
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Detection of human papillomavirus DNA by the hybrid capture assay BJID
Carvalho,Maria Odete O.; Almeida,Ricardo W.; Leite,Fátima M. S.; Fellows,Ilza B.; Teixeira,Mariza H.; Oliveira,Ledy H. S.; Cavalcanti,Silvia M. B..
Human Papillomavirus (HPV) infection is the main cause of cervical cancers and cervical intraepithelial neoplasias (CIN) worldwide. Consequently, it would be useful to evaluate HPV testing to screen for cervical cancer. Recently developed, the second-generation Hybrid Capture (HCA II) test is a non-radioactive, relatively rapid, liquid hybridization assay designed to detect 18 HPV types, divided into high and low-risk groups. We evaluated 1055 women for HPV infection with the HCA II test. Five hundred and ten (48.3%) of these women had HPV infection; 60 (11.8%) had low cancer-risk HPV DNA; 269 (52.7%) had high-risk HPV types and 181 (35.5%) had both groups. Hence, 450 women (88.2%) in this HPV-infected group had at least one high risk HPV type, and were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: HPV; SIL; Cancer; Hybrid capture.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000200004
Registros recuperados: 3
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