|
|
|
|
|
| Zhang,Zhiqun; Zhong,Ying; Li,Xiaoxia; Huang,Xianmei; Du,Lizhong. |
| This study investigates the effect of the overexpression of the placental growth factor (PGF) and hyperoxia on lung development and determines whether anti-PGF antibody ameliorates hyperoxia-mediated impairment of lung development in newborn rats. After exposure to normoxic conditions for seven days, newborn rats subjected to normoxia were intraperitoneally or intratracheally injected with physiological saline, adenovirus-negative control (Ad-NC), or adenovirus-PGF (Ad-PGF) to create the Normoxia, Normoxia+Ad-NC, and Normoxia+Ad-PGF groups, respectively. Newborn rats subjected to hyperoxia were intraperitoneally injected with physiological saline or anti-PGF antibodies to create the Hyperoxia and Hyperoxia+anti-PGF groups, respectively. Our results... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bronchopulmonary dysplasia; Anti-PGF antibody; Newborn rats; Hyperoxia; Lung tissue injury. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000200604 |
| |
|
| |
|
|
| Mataloun,M.M.G.B.; Leone,C.R.; Mascaretti,R.S.; Dohlnikoff,M.; Rebello,C.M.. |
| Several factors are associated with bronchopulmonary dysplasia. Among them, hyperoxia and lung immaturity are considered to be fundamental; however, the effect of malnutrition is unknown. Our objective was to evaluate the effects of 7 days of postnatal malnutrition and hyperoxia on lung weight, volume, water content, and pulmonary morphometry of premature rabbits. After c-section, 28-day-old New Zealand white rabbits were randomized into four groups: control diet and room air (CA, N = 17), control diet and ≥95% O2 (CH, N = 17), malnutrition and room air (MA, N = 18), and malnutrition and ≥95% O2 (MH, N = 18). Malnutrition was defined as a 30% reduction of all the nutrients provided in the control diet. Treatments were maintained for 7 days, after which... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Postnatal malnutrition; Hyperoxia; Lung development; Rabbit. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000700004 |
| |
|
|
| Person, Jeannine; Pichavant, Karine; Vacher, Coralie; Le Bayon, Nicolas; Severe, Armelle; Boeuf, Gilles. |
| Effects of O-2 supersaturation on metabolism and growth were studied in juvenile turbot (Scophthalmus maximus L.). When fish were reared for 30 days in water containing O-2 at 147% or 223% air saturation, there were no significant differences in food intake, growth, food conversion or protein utilization compared to fish exposed to normoxia (100% air saturation in water outlet). Exposure to hyperoxia resulted in increased body fat deposition. Daily rates of O-2 consumption of resting fish were not affected by O-2-concentrations, and there were no significant differences in rates of nitrogenous excretion among fish exposed to the different O-2-concentrations. Turbot tolerated severe hyperoxia, 350% air saturation, for 10 days.There were changes in acid-base... |
| Tipo: Text |
Palavras-chave: Ion regulation; Acid base; Metabolism; Growth; Hyperoxia; Turbot. |
| Ano: 2002 |
URL: http://archimer.ifremer.fr/doc/2002/publication-627.pdf |
| |
|
|
|
