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	Provedor de dados BJMBR (2) Biol. Res. (1) BABT (1) Autor Coimbra,C.G. (1) Durigan,João Luiz Quagliotti (1) Gosho,Masahiko (1) Iwaki,Masayoshi (1) Munin,Flávia Simone (1) Oliveira,Nuno Miguel Lopes de (1) Salvini,Tania de Fátima (1) Schwantes,Maria Luiza Barcelos (1) Takeyama,Masayuki (1) Yoneda,Masahiko (1) Zako,Masahiro (1) Mais... Palavra-chave Hypothermia (4) Age-related macular degeneration (AMD) (1) Apnea test (1) Brain death (1) Cerebral ischemia (1) Cryotherapy (1) Dexamethasone (1) Enzymatic analysis (1) Ethanol (1) Glucocorticoids (1) Intracranial pressure (1) Ischemic penumbra (1) Muscle injury (1) Pigment epithelium-derived factor (PEDF) (1) Rats (1) Rehabilitation (1) Retinal pigment epithelium (RPE) (1) Thrombolysis (1) Tibialis anterior (1) Traumatic brain injury (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Journal article (1) Ano 2015 (1) 2013 (1) 1999 (1) 1997 (1) País Brazil (3) Chile (1) Idioma Inglês (4)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Decreased VEGF-A and sustained PEDF expression in a human retinal pigment epithelium cell line cultured under hypothermia Biol. Res. Takeyama,Masayuki; Yoneda,Masahiko; Gosho,Masahiko; Iwaki,Masayoshi; Zako,Masahiro. BACKGROUND: Previous reports have described a decrease in retinal temperature and clinical improvement of wet age-related macular degeneration (AMD) after vitrectomy. We hypothesized that the retinal temperature decrease after vitrectomy plays a part in the suppression of wet AMD development. To test this hypothesis, we evaluated the temperature dependence of the expression of vascular endothelial growth factor-A (VEGF-A) and in vitro angiogen-esis in retinal pigment epithelium (RPE). RESULTS: We cultured ARPE-19 cells at 37, 35, 33 and 31°C and measured the expression of VEGF-A, VEGF-A splicing variants, and pigment epithelium-derived factor (PEDF). We performed an in vitro tube formation assay. The dehydrogenase activity was also evaluated at each... Tipo: Journal article Palavras-chave: Age-related macular degeneration (AMD); Hypothermia; Pigment epithelium-derived factor (PEDF); Retinal pigment epithelium (RPE); Vascular endothelial growth factor (VEGF); Vitrectomy. Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100042 The effect of intermittent cryotherapy on the activities of citrate synthase and lactate dehydrogenase in regenerating skeletal muscle BABT Oliveira,Nuno Miguel Lopes de; Durigan,João Luiz Quagliotti; Munin,Flávia Simone; Schwantes,Maria Luiza Barcelos; Salvini,Tania de Fátima. This study examined the effect of three sessions of cryotherapy (three sessions of 30 minutes applied each 2 h) and muscle compression in the regenerating skeletal muscle of the rats. The middle belly of tibialis anterior muscle was injured by a frozen iron bar and received one of the following intervention: injury + cryotherapy (treated with cryotherapy); injury + placebo (sand pack), and injury (I).The enzymatic activities of citrate synthase (CS) and lactate dehydrogenase (LDH) were measured in the presence of 1mM or 10mM pyruvate. The ANOVA and Tukey's test (p<0.05) were performed for the statistical analysis. In summary, the intermittent sessions of cryotherapy, associated to muscle compression and applied immediately after the primary muscle... Tipo: Info:eu-repo/semantics/article Palavras-chave: Cryotherapy; Muscle injury; Enzymatic analysis; Hypothermia; Tibialis anterior; Rehabilitation. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000100008 Implications of ischemic penumbra for the diagnosis of brain death BJMBR Coimbra,C.G.. The data reviewed here suggest the possibility that a global reduction of blood supply to the whole brain or solely to the infratentorial structures down to the range of ischemic penumbra for several hours or a few days may lead to misdiagnosis of irreversible brain or brain stem damage in a subset of deeply comatose patients with cephalic areflexia. The following proposals are advanced: 1) the lack of any set of clinically detectable brain functions does not provide a safe diagnosis of brain or brain stem death; 2) apnea testing may induce irreversible brain damage and should be abandoned; 3) moderate hypothermia, antipyresis, prevention of arterial hypotension, and occasionally intra-arterial thrombolysis may contribute to good recovery of a possibly... Tipo: Info:eu-repo/semantics/article Palavras-chave: Ischemic penumbra; Cerebral ischemia; Intracranial pressure; Traumatic brain injury; Brain death; Hypothermia; Thrombolysis; Apnea test. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001200005 Ethanol-induced hypothermia in rats is antagonized by dexamethasone BJMBR The effect of dexamethasone on ethanol-induced hypothermia was investigated in 3.5-month old male Wistar rats (N = 10 animals per group). The animals were pretreated with dexamethasone (2.0 mg/kg, ip; volume of injection = 1 ml/kg) 15 min before ethanol administration (2.0, 3.0 and 4.0 g/kg, ip; 20% w/v) and the colon temperature was monitored with a digital thermometer 30, 60 and 90 min after ethanol administration. Ethanol treatment produced dose-dependent hypothermia throughout the experiment (-1.84 ± 0.10, -2.79 ± 0.09 and -3.79 ± 0.15oC for 2.0, 3.0 and 4.0 g/kg ethanol, respectively, 30 min after ethanol) but only the effects of 2.0 and 3.0 g/kg ethanol were significantly antagonized (-0.57 ± 0.09 and -1.25 ± 0.10, respectively, 30 min after ethanol)... Palavras-chave: Ethanol; Dexamethasone; Hypothermia; Glucocorticoids; Rats. Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000100011 Registros recuperados: 4 Primeira ... 1 ... Última

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