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	Provedor de dados 56 (1) 77 (1) Autor Almeida Barbosa Jr.,Aryon de (1) Arruda,Sergio (1) Azevedo Duarte,Tonya (1) Ding,X. (1) Ji,X. (1) Song,C. (1) Yi,L. (1) Zeng,Y. (1) Zhu,K. (1) Mais... Palavra-chave IFN-g (2) Baicalin (1) Experimental autoimmune encephalomyelitis (1) Granuloma (1) IL-4 (1) Morphometry (1) Mycobacterium (1) Neurologic score (1) Tuberculosis (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Journal article (1) Ano 2007 (1) 2005 (1) País Brazil (1) Chile (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Baicalin reduces the severity of experimental autoimmune encephalomyelitis 56 Zeng,Y.; Song,C.; Ding,X.; Ji,X.; Yi,L.; Zhu,K.. Scutellaria baicalensis Georgi is one of the important medicinal herbs widely used for the treatment of various inflammatory diseases in Asia. Baicalin (BA) is a bioactive anti-inflammatory flavone found abundantly in Scutellaria baicalensis Georgi. To explore the therapeutic potential of BA, we examined the effects of systemic administration of the flavone (5 and 10 mg/kg, ip) on relapsing/remitting experimental autoimmune encephalomyelitis (EAE) induced by proteolipid protein 139-151 in SJL/J mice, an experimental model of multiple sclerosis. The mice treated with PBS or BA at day -1 and for 3 consecutive days were observed daily for clinical signs of disease up to 60 days after immunization. In the PBS-EAE group, neurological scores were: incidence... Tipo: Info:eu-repo/semantics/article Palavras-chave: Experimental autoimmune encephalomyelitis; Baicalin; IFN-g; IL-4; Neurologic score. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000700016 Morphometric Analysis of Granulomas Induced by Mycobacterium bovis Suggests an Influence of IFN-Gamma on the Generation and Modulation upon Granulomatous Inflammatory Response in the Different Tissues 77 Azevedo Duarte,Tonya; Almeida Barbosa Jr.,Aryon de; Arruda,Sergio. There is evidence in both human and experimental infection caused by Mycobacterium tuberculosis, that immunologic factors influence susceptibility to infection and the progress of the disease. The present study aims to evaluate the role of IFN- g upon inflammatory granulomatous response against M. bovis. To pursue that, C57BL/6 mice lacking the genes for synthesis of IFN- g (IFN- g-/-) and their wild-type counterparts (IFN- g+/+) were intravenously inoculated with M. bovis. The ability of M. bovis to survive and replicate in the liver and lungs was evaluated by counting colony-forming unit (CFU). The histopathological features of granulomatous inflammatory response in the liver and lungs were analyzed during the infection by M. bovis. Granuloma parameters... Tipo: Journal article Palavras-chave: Morphometry; Mycobacterium; Tuberculosis; IFN-g; Granuloma. Ano: 2005 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022005000400006 Registros recuperados: 2 Primeira ... 1 ... Última

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