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| Registros recuperados: 28 | |
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| RIBEIRO,Suzana Cardoso; CASTELO,Antonielson Silva; SILVA,Bruna Marjara Picanço da; CUNHA,Andreza da Silva; PROIETTI JÚNIOR,Aldo Aparecido; OBA-YOSHIOKA,Eliane Tie. |
| ABSTRACTIn fish farmings, diseases can be reduced by using immunostimulants. The aim of this study was to evaluate the immunostimulant potential of Mentha piperita in tambaqui fed with 0, 0.5, 1.0 and 1.5% of oil per kg of commercial fish feed. The fish were inoculated with Aeromonas hydrophila to challenge them. Hematological and biochemical parameters were determined after 30 days of feeding and seven days after the challenge. There was no mortality and M. piperita oil did not influence fish production parameters. However, blood hemoglobin concentration (Hb) increased in the fish fed with 0.5 and 1.5% of oil per kg of diet; albumin increased in those fed with 1.0%; cholesterol increased in all groups with oil; and triglycerides increased in those fed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Immune system; Natural product; Bacterial challenge; Biochemistry. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672016000100099 |
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| Fernandes, Jovanir Inês Müller; Universidade Federal do Paraná; Rosa, Daniela Dalla; UFPR - Palotina; Ribeiro, Mayra Vissotto; UFPR-Palotina; Lima, Edna Tereza de; UFPR - Palotina; Fernandes, Nelson Luis Mello; UFPR - Palotina. |
| O estudo foi realizado com o objetivo de avaliar o efeito da suplementação de Arginina (Arg) sobre a resposta imune humoral e o desenvolvimento dos órgãos linfoides de frangos de corte imunizados contra a Doença de Gumboro. Foram utilizados 640 pintos de corte, distribuídos aleatoriamente em um delineamento inteiramente casualizado com quatro tratamentos (1. Controle, 2. Imunização, 3. Imunização + suplementação de L-Arg e 4. Suplementação de L-Arg.) e oito repetições de 20 aves cada. As aves dos tratamentos 3 e 4 foram imunizadas no 16° dia, contra a Doença de Gumboro (cepa intermediária plus). Amostras de soro das aves com 14, 21, 28 e 35 dias de idade foram analisadas por ELISA para detecção de título de anticorpos contra a Doença de Gumboro e... |
| Tipo: Pesquisa de campo |
Palavras-chave: 5.04.03.01-0 Aminoácido; Doença infecciosa da Bursa de Fabrício; Sistema imune; Título de anticorpos; Bolsa cloacal Nutrição animal amino acid; Infectious bursal disease; Immune system; Antibody titers; Cloacal bursa. |
| Ano: 2011 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/9738 |
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| Fernandes, Jovanir Inês Müller; Universidade Federal do Paraná; Murakami, Alice Eiko; UEM. |
| Due to the lack of a complete urea cycle, uricotelic species, such as broilers, are not able to synthesize de novo arginine (Arg), thus depending exclusively on dietary Arg. High levels of dietary lysine (Lys) increase the demand for Arg because of the antagonistic relationship between these amino acids. The Arg-Lys antagonism promotes an expressive increase in the renal Arg activity and consequently induces the degradation of Arg and the decrease in the activity of glycine amidinotransferase, an enzyme that uses Arg in the synthesis of muscle creatin. Arg is considered an important modulator of immunological and physiological processes. The degradation of Arg produces ornithine, a precursor of polyamines that are key to cell division, DNA synthesis, and... |
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Palavras-chave: Carbamoyl phosphatase synthetase; Creatine; Immune system; Nitric oxide; Polyamines; Urea cycle carbamoyl phosphatase synthetase; Creatine; Immune system; Nitric oxide; Polyamines; Urea cycle. |
| Ano: 2010 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/10990 |
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| KLOSTERHOFF,MARTA C.; PEREIRA JÚNIOR,JOABER; RODRIGUES,RICARDO V.; GUSMÃO,EMELINE P.; SAMPAIO,LUÍS A.; TESSER,MARCELO B.; ROMANO,LUIS A.. |
| ABSTRACT In the present study was evaluated the ontogenic of immunocompetent organs of cobia up to 53 days after hatching (dah) through histology and immunohistochemistry techniques. The kidney was the first lymphohematopoietic organ to appear, at 1 dah, followed by the spleen at 5 dah and the thymus at 7 dah. The first CD3 receptors on the lymphocytes were observed in 27% of the thymic tissue at 7 dah and in 99% at 53 dah. The phenotypic expression of CD3 receptors was registered in 10% of the kidney at 8 dah and in 32% at 53 dah. CD4 receptors were observed in 5% and 63% of the thymic area at 7 and 53 dah, respectively. In the kidney, T4 lymphocytes were first observed at 13 dah in 9% of the organ and in 28% at 53 dah, defining the functional development... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cobia; Immune system; Ontogeny; Immunohistochemistry; Lymphoid organs. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000502111 |
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| Pavanelli,Wander Rogério; Gutierrez,Fredy Roberto Salazar; Silva,Jean Jerley Nogueira da; Costa,Ivete Conchon; Menezes,Maria Claudia Noronha Dutra de; Oliveira,Francisco José de Abreu; Itano,Eiko Nakagawa; Watanabe,Maria Angélica Ehara. |
| Nitric oxide (NO) is a free radical synthesized from L-arginine by different isoforms NO-synthases. NO possesses multiple and complex biological functions. NO is an important mediator of homeostasis, and changes in its generation or actions can contribute or not to pathological states. The knowledge of effects of NO has been not only important to our understanding of immune response, but also to new tools for research and treatment of various diseases. Knowing the importance of NO as inflammatory mediator in diverse infectious diseases, we decided to develop a revision that shows the participation/effect of this mediator in immune response induced against Giardia spp. Several studies already demonstrated the participation of NO with microbicidal and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nitric oxide; Immune system; Giardiasis. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000600010 |
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| Milan-Mattos,J.C.; Anibal,F.F.; Perseguini,N.M.; Minatel,V.; Rehder-Santos,P.; Castro,C.A.; Vasilceac,F.A.; Mattiello,S.M.; Faccioli,L.H.; Catai,A.M.. |
| The term inflammaging is now widely used to designate the inflammatory process of natural aging. During this process, cytokine balance is altered, presumably due to the loss of homeostasis, thus contributing to a greater predisposition to disease and exacerbation of chronic diseases. The aim of the study was to analyze the relationship between pro-inflammatory markers and age in the natural aging process of healthy individuals. One hundred and ten subjects were divided into 5 groups according to age (22 subjects/group). Interleukin-6 (IL-6) and tumor necrosis factor α (TNF-α) were quantified using the ELISA method. High-sensitivity C-reactive protein (hsCRP) was analyzed by turbidimetry according to laboratory procedures. The main findings of this study... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Natural aging; Inflammaging; Immune system; HsCRP; IL-6. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000900601 |
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| Pompéia,C.; Lopes,L.R.; Miyasaka,C.K.; Procópio,J.; Sannomiya,P.; Curi,R.. |
| Fatty acids have various effects on immune and inflammatory responses, acting as intracellular and intercellular mediators. Polyunsaturated fatty acids (PUFAs) of the omega-3 family have overall suppressive effects, inhibiting lymphocyte proliferation, antibody and cytokine production, adhesion molecule expression, natural killer cell activity and triggering cell death. The omega-6 PUFAs have both inhibitory and stimulatory effects. The most studied of these is arachidonic acid that can be oxidized to eicosanoids, such as prostaglandins, leukotrienes and thromboxanes, all of which are potent mediators of inflammation. Nevertheless, it has been found that many of the effects of PUFA on immune and inflammatory responses are not dependent on eicosanoid... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fatty acids; Immune system; Inflammation; Dietary lipids; Leukocytes. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001100001 |
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| Vaz,N.M.; Faria,A.M.C. de; Verdolin,B.A.; Silva Neto,A.F.; Menezes,J.S.; Carvalho,C.R.. |
| Current immunological opinion disdains the necessity to define global interconnections between lymphocytes and regards natural autoantibodies and autoreactive T cells as intrinsically pathogenic. Immunological theories address the recognition of foreignness by independent clones of lymphocytes, not the relations among lymphocytes or between lymphocytes and the organism. However, although extremely variable in cellular/molecular composition, the immune system preserves as invariant a set of essential relations among its components and constantly enacts contacts with the organism of which it is a component. These invariant relations are reflected, for example, in the life-long stability of profiles of reactivity of immunoglobulins formed by normal organisms... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Immunobiology; Immune system; Closure; Network; Autopoiesis; Panama blot. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000100003 |
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| Licinio,J.; Frost,P.. |
| Cytokines are molecules that were initially discovered in the immune system as mediators of communication between various types of immune cells. However, it soon became evident that cytokines exert profound effects on key functions of the central nervous system, such as food intake, fever, neuroendocrine regulation, long-term potentiation, and behavior. In the 80's and 90's our group and others discovered that the genes encoding various cytokines and their receptors are expressed in vascular, glial, and neuronal structures of the adult brain. Most cytokines act through cell surface receptors that have one transmembrane domain and which transduce a signal through the JAK/STAT pathway. Of particular physiological and pathophysiological relevance is the fact... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Central nervous system; Cytokines; Immune system; Neuroendocrine regulation; Fever; Food intake. |
| Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001000003 |
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| Fernandes,C.I.; Llimona,F.; Godoy,L.C.; Negri,E.M.; Pontieri,V.; Moretti,A.I.; Fernandes,T.R.; Soriano,F.G.; Velasco,I.T.; Souza,H.P.. |
| Shock and resuscitation render patients more susceptible to acute lung injury due to an exacerbated immune response to subsequent inflammatory stimuli. To study the role of innate immunity in this situation, we investigated acute lung injury in an experimental model of ischemia-reperfusion (I-R) followed by an early challenge with live bacteria. Conscious rats (N = 8 in each group) were submitted to controlled hemorrhage and resuscitated with isotonic saline (SS, 0.9% NaCl) or hypertonic saline (HS, 7.5% NaCl) solution, followed by intratracheal or intraperitoneal inoculation of Escherichia coli. After infection, toll-like receptor (TLR) 2 and 4 mRNA expression was monitored by RT-PCR in infected tissues. Plasma levels of tumor necrosis factor α and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toll-like receptors; Immune system; Pneumonia; Escherichia coli; Neutrophils. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001000004 |
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| Wang,Chun-jie; Yu,Siriguleng; Ao-ri-ge-le,; Jia,De-gang; Yao,Hong-qiang; Zhao,Huai-ping; Lillehoj,H.S.; Si-mu-ji-de,; Postnikoff,Andrew CL; Xu,Si-ri-gu-leng. |
| Two-day-old specific pathogen-free (SPF) chickens were divided into two groups. Group I was inoculated orally with fowl adenovirus VIII (FAV-VIII). Group II served as a negative control. Chickens were investigated at various days post-inoculation (dpi) by flow cytometric analysis for changes in T lymphocyte subpopulations in immune system and blood. In the thymus, CD3+ T lymphocytes were increased at 25 dpi, with significant increases in the FAV infected noted at 1, 12, 20dpi (p<0.05). This was accompanied by a corresponding increase of CD4+ and CD8+ T lymphocytes. In the spleen, CD3+ and CD4+ T lymphocytes were increased significantly at 30 dpi (p<0.01) whereas CD8+ and TCR γ δ+ T lymphocytes were decreased at 1 (p<0.05), 30 dpi (p<0.01). An... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cell mediated immune competency; Fowl adenovirus VIII; Immune system; Peripheral blood; T lymphocyte subpopulations. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000400007 |
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| Taghiloo,Saeid; Allahmoradi,Esmaeil; Sadeghian-Kiadehi,Seyedeh Forough; Omrani-Nava,Versa; Nazar,Eisa; Ebrahimzadeh,Mohammad Ali. |
| Donkey’s milk represents a good alternative to human milk because of its chemical characteristics similar to those of human’s. In present study, the pro- and anti-inflammatory effects of donkey’s milk were evaluated on peripheral blood mononuclear cells (PBMCs). PBMCs were isolated from 12 young and 12 aged normal subjects. PBMCs were cultured with or without the optimal and non-cytotoxic dose of pasteurized donkey’s milk, and polymyxin B was used to inhibit the possible endotoxin contamination. Following 18 hours incubation, culture supernatants were harvested to measure the secreted Tumor necrosis factor-α (TNF-α), Interleukin-6 (IL-6), Interleukin-8 (IL-8) and Interleukin-10 (IL-10) by ELISA. Donkey’s milk significantly increased TNF-α (p= 0.01), IL-8... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Donkey’s milk; ELISA; Immune system; Aged subject; Cytokine. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100607 |
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| Registros recuperados: 28 | |
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