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	Provedor de dados Biological Sciences (1) Autor Benevides, Norma Maria Barros (1) Holanda, Márjory Lima (1) Pereira, Maria Gonçalves (1) Queiroz, Ismael Nilo Lino de (1) Quinderé, Ana Luíza Gomes (1) Rodrigues, José Ariévilo Gurgel (1) Mais... Palavra-chave Antithrombotic agent (1) Bioactivities (1) Gelidiella acerosa (1) In vivo toxicity (1) Polysulfated (1) Rhodophyta (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2014 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Inhibition of coagulation proteases and thrombosis and sub-chronic toxicological study of a sulfated polysaccharidic fraction from the red alga Gelidiella acerosa Biological Sciences Queiroz, Ismael Nilo Lino de; Rodrigues, José Ariévilo Gurgel; Quinderé, Ana Luíza Gomes; Holanda, Márjory Lima; Pereira, Maria Gonçalves; Benevides, Norma Maria Barros. Metabolites isolated from Gelidiella species (Rhodophyta) have been few studied. We evaluated a sulfated polysaccharidic fraction from G. acerosa collected from two Brazilian beaches on the northwestern coast of Brazil (Flecheiras-F and Pedra Rachada-PR) on coagulation proteases and thrombosis. Their toxicity in vivo was also assessed. Enzymatic extractions yielded 1.40%, and similar chromatographic profiles (DEAE-cellulose) were obtained, with fractions (Ga-I→V) containing differences among the relative proportions of sulfate (5-42%), and revealing charge density patterns by electrophoresis. Ga-IV-PR had a discrete effect (3.01 IU mg-1) on normal human coagulation compared with heparin (193 IU mg-1) and was tested on coagulation proteases (thrombin and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Rhodophyta; Polysulfated; Gelidiella acerosa; Antithrombotic agent; Bioactivities; In vivo toxicity. Ano: 2014 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/23704 Registros recuperados: 1 Primeira ... 1 ... Última

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