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	Provedor de dados BJPS (1) Autor Catherine,Dorcas Pinky (1) Nair,Keerthi G. S (1) Ravikumar,Yamuna (1) Sekar,Akshya (1) Velmurugan,Ramaiyan (1) Palavra-chave Gastric cancer (1) In-vitro (1) In-vivo (1) Nanoparticle (1) Paclitaxel (1) Spirulina (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2020 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Paclitaxel and spirulina co-loaded polymeric nanoparticles: in-vitro and in-vivo anticancer study BJPS Ravikumar,Yamuna; Catherine,Dorcas Pinky; Nair,Keerthi G. S; Sekar,Akshya; Velmurugan,Ramaiyan. Paclitaxel spirulina nanoparticles were said to have promising anticancer activity against gastric cancer. Nanoparticles of paclitaxel-spirulina were prepared for treating gastric cancer using precipitation technique. The synergistic anticancer efficiency againstMKN45 cells retains when the paclitaxel and spirulina were encapsulated into nanoparticles. To increase the site specific delivery, intra-tumoral administration was carried in the in vivo evaluation. There was an increase in overall survival in an MKN45-transplanted mice model and notable improvement in anti-tumour efficacy when paclitaxel-spirulina nanoparticles were delivered through intra-tumoral administration. The further investigation of overall anticancer mechanism of these nanoparticles is... Tipo: Info:eu-repo/semantics/article Palavras-chave: Paclitaxel; Spirulina; Nanoparticle; In-vitro; In-vivo; Gastric cancer. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100642 Registros recuperados: 1 Primeira ... 1 ... Última

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