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Association between interleukin 6 -174 G/C promoter gene polymorphism and runners' responses to the dietary ingestion of antioxidant supplementation based on pequi (Caryocar brasiliense Camb.) oil: a before-after study Genet. Mol. Biol.
Miranda-Vilela,Ana Luisa; Ribeiro,Ieler Ferreira; Grisolia,Cesar Koppe.
Abstract Exercise is a double-edged sword: when practiced in moderation, it increases the expression of antioxidant enzymes, but when practiced strenuously it causes oxidative stress and cell damage. In this context, polymorphisms in the interleukin (IL)-6 gene should be investigated better because they can influence performance, at least in exercise that generates oxidative stress and leads to muscular injuries with consequent inflammation. In this work, we investigated the influence of IL-6 –174 G/C polymorphism on tissue damage and inflammation markers, lipid peroxidation, hemogram and lipid profile of runners before and after ingestion of 400 mg of pequi oil in capsules supplied daily for 14 consecutive days. The IL-6 genotypes were associated with...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antioxidant supplementation; Exercise-induced oxidative damage; Inflammatory markers; Nutrigenetics; Nutrigenomics.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000400554
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C-reactive protein in acute coronary syndrome: association with 3-year outcomes BJMBR
Schaan,B.D.; Pellanda,L.C.; Maciel,P.T.; Duarte,E.R.; Portal,V.L..
Inflammatory markers have been associated with clinical outcome in patients with acute coronary syndrome (ACS). The present study evaluated the role of high-sensitivity C-reactive protein (CRP) measurements as a predictor of late cardiovascular outcomes after ACS. One hundred and ninety-nine ACS patients in a Coronary Care Unit from March to November 2002 were included and were reassessed clinically after ~3 years. Clinical variables and CRP levels were evaluated as predictors of major cardiovascular events (MACE, defined as the occurrence of cardiac death, ischemic stroke or myocardial infarction) and mortality. Statistical analyses included Cox multivariable analysis and survival curves (Kaplan-Meier). Of the 199 patients, 11 died within 1 month (5.5%)....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute coronary syndromes; Inflammatory markers; C-reactive protein; Major cardiovascular events; Mortality.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001200019
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