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Heterogeneous periodicity of drosophila mtDNA: new refutations of neutral and nearly neutral evolution Biol. Res.
Valenzuela,Carlos Y.
We found a consistent 3-site periodicity of the X²9 values for the heterogeneity of the distribution of the second base in relation to the first base of dinucleotides separated by 0 (contiguous), 1, 2, 3 ... 17 (K) nucleotide sites in Drosophila mtDNA. Triplets of X²9 values were found where the first was over 300 and the second and third ranged between 37 and 114 (previous studies). In this study, the periodicity was significant until separation of 2011K, and a structure of deviations from randomness among dinucleotides was found. The most deviant dinucleotides were G-G, G-C and C-G for the first, second and third element of the triplet, respectively. In these three cases there were more dinucleotides observed than expected. This inter-bases correlation...
Tipo: Journal article Palavras-chave: DNA organization; Non-protein-coding evolution; Ordered nucleotide sequences; Inter-base associations; Refutation of neutralism.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000300010
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