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	Provedor de dados BJMBR (1) J. Venom. Anim. Toxins incl. Trop. Dis. (1) Autor Bannwart,C.F. (1) Caligiuri,M.A. (1) Carson,W. (1) Nakaira,E.T. (1) Peraçoli,M.T.S. (1) Sartori,A. (1) Mais... Palavra-chave Innate immunity (2) Interleukin-15 (2) Gamma interferon (1) Interleukin-12 (1) Microbial infections (1) Natural killer cell (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2007 (1) 1998 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Interleukin-15: its role in microbial infections J. Venom. Anim. Toxins incl. Trop. Dis. Bannwart,C.F.; Nakaira,E.T.; Sartori,A.; Peraçoli,M.T.S.. Interleukin-15 (IL-15) is a pleiotropic cytokine which regulates the proliferation, survival and the secretory activities of many distinct cell types in the body. This cytokine is produced by macrophages and many other cell types in response to infectious agents; it controls growth and differentiation of T and B lymphocytes, activation of Natural Killer (NK) and phagocytic cells, and contributes to the homeostasis of the immune system. The present review focuses on the biological and modulatory effects of IL-15 in microbial infections and shows that this cytokine may play a role in the host defense against infections by inducing activation of effector cells from both innate and adaptive immune system. Tipo: Info:eu-repo/semantics/article Palavras-chave: Interleukin-15; Microbial infections; Innate immunity. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000300002 Interleukin-15 as a potential regulator of the innate immune response BJMBR Carson,W.; Caligiuri,M.A.. Interleukin-15 (IL-15) is a newly-discovered cytokine that is produced by activated monocytes early in the course of the innate immune response. IL-15 is able to bind to components of the interleukin-2 receptor (IL-2R) despite the fact that it has no sequence homology with IL-2. IL-15 stimulates human natural killer cell proliferation, cytotoxicity, and cytokine production and can substitute for IL-2 under most conditions. In vitro studies indicate that monocyte-derived IL-15 may be an important determinant of IFN-gamma production by NK cells. In addition, IL-15 is able to promote the survival of natural killer cells under serum-free conditions. The IL-15 receptor is a heterotrimeric complex which is composed of the IL-2Rß and <FONT... Tipo: Info:eu-repo/semantics/article Palavras-chave: Interleukin-15; Interleukin-12; Gamma interferon; Natural killer cell; Innate immunity. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000100001 Registros recuperados: 2 Primeira ... 1 ... Última

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