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	Provedor de dados BJPS (3) Anais da ABC (AABC) (1) Autor Basu,Sanat Kumar (1) GARCIA,JERUSA SIMONE (1) Krishnamoorthy,Balakrishnam (1) Kumar,S. Senthil (1) Mandal,Sanchita (1) Ray,Sarbani Dey (1) SILVA,RENATA CRISTINA (1) Saha,Avik Kumar (1) TREVISAN,MARCELLO G. (1) Tilkan,Müşerref Günseli Yüksel (1) Özdemir,Nurten (1) Mais... Palavra-chave Ionotropic gelation (4) Alginate beads/evaluation (1) Alginate beads/preparation (1) Biopolymer (1) Calcium alginate beads (1) Chitosan (1) Drugs/sustained release (1) Encapsulation (1) Enzymatic activity (1) Flurbiprofen (1) Interpenetrating network (1) Lactase (1) Microsphere (1) Sodium alginate (1) Sodium diclofenac/microsphere (1) Sodium diclofenac/sustained release (1) Trimetazidine dihydrochloride (1) Tripolyphosphate (1) Mais... Tipo do documento Info:eu-repo/semantics/article (4) Ano 2020 (1) 2017 (1) 2013 (1) 2010 (1) País Brazil (4) Idioma Inglês (4)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última β-galactosidase Encapsulated in Carrageenan, Pectin and Carrageenan/Pectin: Comparative Study, Stability and Controlled Release Anais da ABC (AABC) SILVA,RENATA CRISTINA; TREVISAN,MARCELLO G.; GARCIA,JERUSA SIMONE. Abstract The present study investigated the encapsulation of β-galactosidase in carrageenan, pectin and its hybrid hydrogels by using the ionotropic gelation method. The material obtained was characterized by Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TG/DTG) and scanning electron microscopy (SEM). The effects of pH, temperature and storage time were evaluated in terms of the catalytic activity of the free and encapsulated enzyme. Addition studies were conducted evaluating the performance of catalytic activity in vitro conditions. Carrageenan, pectin and hybrid hydrogels presented encapsulation efficiency of 58 ± 1%, 72 ± 1% and 77 ± 2%, respectively. The pectin hydrogel showed the higher β-galactosidase activity in pH and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Biopolymer; Encapsulation; Enzymatic activity; Ionotropic gelation; Lactase. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100905 Investigation of the parameters affecting the release of flurbiprofen from chitosan microspheres BJPS Tilkan,Müşerref Günseli Yüksel; Özdemir,Nurten. ABSTRACT Flurbiprofen (FLB), a NSAID, widely used for preventing pain generally for arthritis or dental problems. In this study, FLB loaded chitosan microspheres were prepared by ionotropic gelation method. In this method, microspheres were formed by dropping chitosan solutions containing FLB into sodium alginate solutions including sodium tripolyphosphate (TPP). A variety of formulation parameters like drug:polymer ratio, drug concentration, polymer’s molecular weight, polymer concentration, pH and the concentration of TPP solutions, drying method and stirring time were analyzed. The dissolution studies were performed in a shaking water bath in pH 7.4 phosphate buffer saline (PBS) at 37 °C. Laser diffractometer was used for particle size analysis, and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Flurbiprofen; Chitosan; Tripolyphosphate; Ionotropic gelation; Microsphere. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000400621 Development and evaluation of calcium alginate beads prepared by sequential and simultaneous methods BJPS Mandal,Sanchita; Kumar,S. Senthil; Krishnamoorthy,Balakrishnam; Basu,Sanat Kumar. The objective of this study was to develop a sustained release dosage form of Trimetazidine dihydrochloride (TMZ) using a natural polymeric carrier prepared in a completely aqueous environment. TMZ was entrapped in calcium alginate beads prepared with sodium alginate by the ionotropic gelation method using calcium chloride as a crosslinking agent. The drug was incorporated either into preformed calcium alginate gel beads (sequential method) or incorporated simultaneously during the gelation stage (simultaneous method). The beads were evaluated for particle size and surface morphology using optical microscopy and SEM, respectively. Beads produced by the sequential method had higher drug entrapment. Drug entrapment in the sequential method was higher with... Tipo: Info:eu-repo/semantics/article Palavras-chave: Sodium alginate; Calcium alginate beads; Trimetazidine dihydrochloride; Ionotropic gelation. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000400021 Effect of cross-linked biodegradable polymers on sustained release of sodium diclofenac-loaded microspheres BJPS Saha,Avik Kumar; Ray,Sarbani Dey. The objective of this study was to formulate an oral sustained release delivery system of sodium diclofenac(DS) based on sodium alginate (SA) as a hydrophilic carrier in combination with chitosan (CH) and sodium carboxymethyl cellulose (SCMC) as drug release modifiers to overcome the drug-related adverse effects and to improve bioavailability. Microspheres of DS were prepared using an easy method of ionotropic gelation. The prepared beads were evaluated for mean particle size, entrapment efficiency, swelling capacity, erosion and in-vitro drug release. They were also subjected to various studies such as Fourier Transform Infra-Red Spectroscopy (FTIR) for drug polymer compatibility, Scanning Electron Microscopy for surface morphology, X-ray Powder... Tipo: Info:eu-repo/semantics/article Palavras-chave: Alginate beads/preparation; Alginate beads/evaluation; Drugs/sustained release; Interpenetrating network; Sodium diclofenac/microsphere; Sodium diclofenac/sustained release; Ionotropic gelation. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502013000400028 Registros recuperados: 4 Primeira ... 1 ... Última

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