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Kidney involvement in leishmaniasis — a review BJID
Silva Junior,Geraldo Bezerra da; Barros,Elvino José Guardão; Daher,Elizabeth De Francesco.
Leishmaniasis is an infectious disease caused by protozoa of the genus Leishmania transmitted by insects of the genus Lutzomyia sp. or Phlebotomus sp. The main syndromes are cutaneous leishmaniasis, mucocutaneous leishmaniasis, visceral leishmaniasis (kala-azar) and post-kala-azar dermal leishmaniasis. This article reviews kidney involvement in cutaneous and visceral leishmaniasis, highlighting the aspects of their pathophysiology, clinical manifestations, histopathological findings, outcome and treatment.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Visceral leishmaniasis; American cutaneous leishmaniasis; Kala-azar; Kidney disease.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000400434
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Association between syndecan-1 and renal function in adolescents with excess weight: evidence of subclinical kidney disease and endothelial dysfunction BJMBR
Saboia,Z.M.R.M.; Meneses,G.C.; Martins,A.M.C.; Daher,E.F.; Silva Junior,G.B..
Excess weight (overweight and obesity) is associated with kidney and cardiovascular disease. The aim of this study was to investigate the association between syndecan-1 and renal function among adolescents with excess weight. A total of 56 students from a public school at Fortaleza, CE, Brazil, were investigated. The adolescents were submitted to anthropometric evaluation, including weight, height, blood pressure and body mass index. Blood and urine samples were collected for the determination of serum lipids (total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, triglycerides), and the endothelial injury biomarker syndecan-1. Participants' mean age was 16±1 years (range 14-19 years), and 68% were females. Overweight...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Obesity; Overweight; Biomarkers; Kidney disease; Endothelium; Adolescents.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000300606
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Evaluation of renal function in sickle cell disease patients in Brazil BJMBR
Silva Junior,G.B.; Libório,A.B.; Vieira,A.P.F.; Bem,A.X. Couto; Lopes Filho,A.S.; Figueiredo Filho,A.C.; Guedes,A.L.M.O.; Souza,J.H.; Costa,C.M.B.E.; Costa,R.; Daher,E.F..
The objective of this study was to investigate renal function in a cohort of 98 patients with sickle cell disease (SCD) followed up at a tertiary hospital in Brazil. Clinical and laboratory characteristics at the time of the most recent medical examination were analyzed. Renal function was evaluated by the estimation of glomerular filtration rate (GFR) by the criteria of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI). We compared patients with normal GFR to patients with decreased GFR (<60 mL·min-1·(1.73 m²)-1) and hyperfiltration (&gt;120 mL·min-1·(1.73 m²)-1). Comparison between patients according to the use of hydroxyurea and comparison of clinical and laboratory parameters according to GFR were also carried out. Average patient...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Sickle cell disease; Kidney disease; Glomerular filtration rate; Creatinine; Chronic kidney disease; Hydroxyurea.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000700013
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Renal injury in female dogs with pyometra Ciência Rural
Figueiredo,Mariana da Silva; Malm,Christina; Mamão,Leonardo Dias; Oliveira,Juliana de; Veado,Júlio César Cambraia; Costa,Mariana Pádua; Valente,Pâmela Cristina Lopes Gurgel; Horta,Rodrigo dos Santos; Castro,Marina Lopes; Castro,Aline Gomes de; Sbaraini,Leila; Souza,Eliana Matias de.
ABSTRACT: Pyometra is a common disease in intact female dogs and can cause glomerulopathy and tubular injury. This study aimed to evaluate kidney injury in female dogs with pyometra, as well as progression of the injury during treatment and the markers of this condition. This study analyzed 20 intact female dogs with both clinical and sonographic diagnosis of pyometra. Dogs were treated with intravenous fluids and antibiotics, and an ovariohysterectomy was performed. The following parameters were assessed at eight separate time points: blood pressure; serum creatinine, phosphorus, and urea levels; urinalysis and urinary biochemical parameters [urinary gamma-glutamyl transferase (uGGT) and urinary protein-to-creatinine ratio (UPCR)]; glomerular filtration...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Kidney disease; Kidney function; Urinary GGT; Urinary protein-to-creatinine ratio; Glomerular filtration rate.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000500603
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Mesenchymal stem cell therapy promotes the improvement and recovery of renal function in a preclinical model Genet. Mol. Biol.
Urt-Filho,Antônio; Oliveira,Rodrigo Juliano; Hermeto,Larissa Correa; Pesarini,João Renato; David,Natan de; Cantero,Wilson de Barros; Falcão,Gustavo; Marks,Guido; Antoniolli-Silva,Andréia Conceição Milan Brochado.
Abstract Acute renal failure (ARF) is an extremely important public health issue in need of novel therapies. The present study aimed to evaluate the capacity of mesenchymal stem cell (MSC) therapy to promote the improvement and recovery of renal function in a preclinical model. Wistar rats were used as the experimental model, and our results show that cisplatin (5mg/kg) can efficiently induce ARF, as measured by changes in biochemical (urea and creatinine) and histological parameters. MSC therapy performed 24h after the administration of chemotherapy resulted in normalized plasma urea and creatinine levels 30 and 45d after the onset of kidney disease. Furthermore, MSC therapy significantly reduced histological changes (intratubular cast formation in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bone marrow; Chemotherapy; Nephrotoxicity; Kidney disease; Tissue regeneration.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000200290
Registros recuperados: 5
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