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	Provedor de dados BJMBR (2) Autor Cravo,S.L. (1) Dantas,M.A. (1) Futuro Neto,H.A. (1) Lopes,O.U. (1) Pires,J.G.P. (1) Russo,A.K. (1) Silva,N.F. (1) Tolentino-Silva,F.P. (1) Mais... Palavra-chave Kynurenic acid (2) Blood pressure (1) Breathing pattern (1) Cardiorespiratory control (1) Caudal pressor area (1) Electrical stimulation (1) Excitatory amino acid receptors (1) Raphe nuclei (1) Rat (1) Ventral surface of the medulla (1) Ventrolateral medulla (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2002 (1) 1998 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Excitatory amino acid receptor blockade within the caudal pressor area and rostral ventrolateral medulla alters cardiovascular responses to nucleus raphe obscurus stimulation in rats BJMBR Silva,N.F.; Pires,J.G.P.; Dantas,M.A.; Futuro Neto,H.A.. Pressor responses elicited by stimulation of the nucleus raphe obscurus (NRO) depend on the integrity of the rostral ventrolateral medulla (RVLM). Therefore, to test the participation of excitatory amino acid (EAA) receptors in the cardiovascular responses evoked by NRO stimulation (1 ms, 100 Hz, 40-70 µA, for 10 s), the EAA antagonist kynurenic acid (Kyn) was microinjected at different sites in the ventrolateral medullar surface (2.7 nmol/200 nl) of male Wistar rats (270-320 g, N = 39) and NRO stimulation was repeated. The effects of NRO stimulation were: hypertension (deltaMAP = +43 ± 1 mmHg, P<0.01), bradycardia (deltaHR = -30 ± 7 bpm, P<0.01) and apnea. Bilateral microinjection of Kyn into the RVLM, which did not change baseline parameters,... Tipo: Info:eu-repo/semantics/article Palavras-chave: Raphe nuclei; Electrical stimulation; Ventrolateral medulla; Caudal pressor area; Excitatory amino acid receptors; Kynurenic acid; Blood pressure. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001000019 Respiratory effects of kynurenic acid microinjected into the ventromedullary surface of the rat BJMBR Tolentino-Silva,F.P.; Russo,A.K.; Cravo,S.L.; Lopes,O.U.. Several studies demonstrate that, within the ventral medullary surface (VMS), excitatory amino acids are necessary components of the neural circuits involved in the tonic and reflex control of respiration and circulation. In the present study we investigated the cardiorespiratory effects of unilateral microinjections of the broad spectrum glutamate antagonist kynurenic acid (2 nmol/200 nl) along the VMS of urethane-anesthetized rats. Within the VMS only one region was responsive to this drug. This area includes most of the intermediate respiratory area, partially overlapping the rostral ventrolateral medulla (IA/RVL). When microinjected into the IA/RVL, kynurenic acid produced a respiratory depression, without changes in mean arterial pressure or heart... Tipo: Info:eu-repo/semantics/other Palavras-chave: Ventral surface of the medulla; Breathing pattern; Cardiorespiratory control; Kynurenic acid; Rat. Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998001000016 Registros recuperados: 2 Primeira ... 1 ... Última

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