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Health care workers humoral immune response against GLcB, MPT51 and HSPX from Mycobacterium tuberculosis BJID
Reis,Michelle Cristina Guerreiro dos; Rabahi,Marcelo Fouad; Kipnis,André; Junqueira-Kipnis,Ana Paula.
Tuberculosis (TB) is one of the oldest human infectious diseases and one third of the world's population is latently infected. Brazil is an endemic area for TB. One of the most important challenges in TB control is the identification of latently infected individuals. Health Care Workers (HCW) are at high risk of being infected with Mycobacterium tuberculosis and even to become TB latently infected. The aim of this study was to increase knowledge about humoral immune response in TB latently infected individuals. HCW were classified according to their tuberculin skin test (TST), as positive or negative. The antibody response to GLcB, MPT51 and HSPX from Mycobacterium tuberculosis was evaluated. TST negative HCW constituted the majority of those who showed a...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Latent tuberculosis; Infection; Antibodies.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000600006
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Tuberculin skin testing in inflammatory bowel disease patients from an endemic area of Brazil BJID
Cardoso,Ingrid Puig; de Almeida,Neogelia Pereira; Gotardo,Daniela Rosa; Cardeal,Mauricio; Santana,Genoile Oliveira.
Objective:Inflammatory bowel disease (IBD) is a chronic disorder involving the gastrointestinal tract. Immunosuppressive drugs are usually prescribed to treat IBD patients, and this treatment can lead to tuberculosis reactivation. This paper aimed to analyze tuberculin skin test (TST) results in IBD patients at a reference center in Brazil.Methods:We evaluated TST results in IBD patients using a cross-sectional study. We also analyzed the medical records of patients treated at a reference IBD outpatient unit where TST is routinely performed.Results:We reviewed 119 medical records of 57 (47.9%) Crohn's disease (CD), 57 (47.9%) ulcerative colitis (UC) and 5 (4.2%) indeterminate colitis (IC) patients. The mean (SD) age was 43.5 (13.7) years old. TST was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: IBD; TST; Latent tuberculosis.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000100060
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