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Al-Balawi,Hmoud Fares Alkahem; Al-Akel,Ali Sulaiman; Al-Misned,Fahad; Suliman,El Amin Mohamed; Al-Ghanim,Khalid Abdullah; Mahboob,Shahid; Ahmad,Zubair. |
The aim of this work was to study the effects of sub-lethal exposure of lead acetate on the histopathology of the gills, liver, kidney and muscle and its accumulation in these organs of Clarias gariepinus. Results showed that lead accumulation in the tissues of C. gariepinus was dependent on the exposure period and lead concentration. Gills and liver were the predominant storage tissue and the order of accumulation in tissues was gill > liver > kidney > muscle. Some structural changes were observed in different organs, especially in the gills of the fishes exposed to lead acetate. Epithelial hypertrophy and epithelial lifting were apparent in the gills of exposed fishes. The degeneration of cytoplasm and secondary lamellae was also observed.... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Clarias gariepinus; Lead acetate; Accumulation; Histopathology. |
Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000200015 |
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Goulart,E.C.; Pereira,C.A.T.; Garcia,R.C.; Giacomelli,M.B.O.; Rodrigues,A.L.S.. |
Lead has been shown to produce cognitive and motor deficits in young rats that could be mediated, at least in part, by inhibition of the zinc-containing heme biosynthetic enzyme delta-aminolevulinate dehydratase (ALA-D). In the present study we investigated the effects of lead and/or zinc treatment during the second stage of rapid postnatal brain development on brain, kidney and blood ALA-D specific activity, as well as the negative geotaxis behavior of rats. Eight-day-old Wistar rats were injected intraperitoneally with saline, lead acetate (8 mg/kg) and/or zinc chloride (2 mg/kg) daily for five consecutive days. Twenty-four hours after treatment, ALA-D activity was determined in the absence and presence of DL-dithiothreitol (DTT). The negative geotaxis... |
Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Lead acetate; Zinc chloride; Delta-aminolevulinate dehydratase; Negative geotaxis; Postnatal brain growth. |
Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000600014 |
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Deveci,E; Söker,S; Baran,Ö; Tunik,S; Ayaz,E; Deveci,S. |
The purpose of this study was to investigate the ultrastructural effects of lead on the kidney cortex of rats. Wistar Albino rats (180-200g body weight) were divided into a controlled and lead acetate-exposed group. Rats received lead acetate at 500 ppm in their drinking water for 60 days. Both groups were fed with the same standard food, but lead acetate was added to the drinking water. During the experimental period, blood samples were taken from the abdominal aorta of the anesthetised animals. At the end of exposure, body weight and blood lead levels were measured. The kidney tissue samples were prepared and analyzed by light and transmission electron microscopy. Cortical renal tubules show various degenerative changes with focal tubular necrosis... |
Tipo: Journal article |
Palavras-chave: Lead acetate; Kidney cortex; Ultrastructural changes. |
Ano: 2011 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000300067 |
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Bomfim,Kátia Michelle dos Anjos; Garcia,Carlos Alexandre Borges; Reis,Francisco Prado; Palmeira,José Arnaldo Vasconcelos; Scher,Ricardo; de Lucca Júnior,Waldecy; Aragão,José Adeval; Vasconcelos,Francis Lima; Albuquerque Júnior,Ricardo Luiz Cavalcanti; Feitosa,Vera Lúcia Corrêa. |
Lead is one of the heavy metals most used in industry. Poisoning due to long-term lead exposure is known as saturnism, and is an occupational illness that has been known for many years. Lead is highly toxic and can compromise the structural and functional patterns of organs and systems. The aim of this study was to examine the lungs and kidneys of fetuses from female Wistar rats exposed to lead acetate. In this study, the lungs and kidneys of 20 fetuses from female rats that had previously been treated with lead acetate were dissected, fixed, embedded in paraffin and stained with hematoxylin and eosin. Macroscopic changes to the shape, color and consistency of organs from fetuses treated with this heavy metal were observed, in comparison with organs from... |
Tipo: Journal article |
Palavras-chave: Lead acetate; Fetuses; Lung; Kidney. |
Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100021 |
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