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	Provedor de dados BJPS (1) Autor Abreu,Bento João (1) Amaral,Ernani (1) Leite,Luciana Ferreira (1) Oliveira,Débora Lopes (1) Palavra-chave Acidification (1) Bipolar cell (1) Lipophilic styryl dye/use (1) Neuromuscular junction (1) Retina (1) Synaptic vesicle (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2012 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Synaptic vesicle cycling is not impaired in a glutamatergic and a cholinergic synapse that exhibit deficits in acidification and filling BJPS Abreu,Bento João; Leite,Luciana Ferreira; Oliveira,Débora Lopes; Amaral,Ernani. The purpose of the present work was to investigate synaptic vesicle trafficking when vesicles exhibit alterations in filling and acidification in two different synapses: a cholinergic frog neuromuscular junction and a glutamatergic ribbon-type nerve terminal in the retina. These synapses display remarkable structural and functional differences, and the mechanisms regulating synaptic vesicle cycling might also differ between them. The lipophilic styryl dye FM1-43 was used to monitor vesicle trafficking. Both preparations were exposed to pharmacological agents that collapse ΔpH (NH4Cl and methylamine) or the whole ΔµH+ (bafilomycin), a necessary situation to provide the driving force for neurotransmitter accumulation into synaptic vesicles. The results... Tipo: Info:eu-repo/semantics/article Palavras-chave: Synaptic vesicle; Acidification; Lipophilic styryl dye/use; Neuromuscular junction; Bipolar cell; Retina. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000100017 Registros recuperados: 1 Primeira ... 1 ... Última

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