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	Provedor de dados BJMBR (2) Autor Hu,Jing (1) Hu,Yao (1) Jiang,Xiangjun (1) Liu,Pei (1) Niu,Qinghui (1) Yang,Yuling (1) Zhang,Fengjuan (1) Zhang,Mingming (1) Mais... Palavra-chave LncRNA ANRIL (2) Apoptotic pathway (1) BMI1 (1) Coronary artery disease (1) Diagnosis (1) Disease severity (1) Gastric cancer (1) Inflammatory responses (1) MiR-99a (1) Notch/mTOR pathway (1) Overall survival (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2019 (1) 2018 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Diagnostic value of circulating lncRNA ANRIL and its correlation with coronary artery disease parameters BJMBR Hu,Yao; Hu,Jing. This study aimed to detect the expression of the long non-coding RNA (lncRNA) antisense non-coding RNA in the INK4 locus (ANRIL) and evaluate its correlation with disease risk, stenosis degree, inflammation, as well as overall survival (OS) in coronary artery disease (CAD) patients. A total of 230 patients who underwent diagnostic coronary angiography were consecutively recruited and assigned to CAD group (n=125) or control group (n=105) according to presence or absence of CAD. Gensini score was calculated to assess the severity of coronary artery damage. Plasma samples were collected and the expression ANRIL was detected in all participants. High-sensitivity C-reactive protein (hs-CRP), erythrocyte sedimentation rate (ESR), and cytokines including tumor... Tipo: Info:eu-repo/semantics/article Palavras-chave: LncRNA ANRIL; Coronary artery disease; Diagnosis; Disease severity; Inflammatory responses; Overall survival. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000800612 Knockdown of long non-coding RNA ANRIL inhibits tumorigenesis in human gastric cancer cells via microRNA-99a-mediated down-regulation of BMI1 BJMBR Liu,Pei; Zhang,Mingming; Niu,Qinghui; Zhang,Fengjuan; Yang,Yuling; Jiang,Xiangjun. Long non-coding RNA antisense non-coding RNA in the INK4 locus (ANRIL) has been reported to promote tumorigenesis via regulating microRNA (miR)-99a in gastric cancer cells. However, the role of each component involved in it is still not well understood. This study aimed to verify the role of ANRIL in gastric cancer as well as the underlying mechanisms. ANRIL levels in clinical gastric cancer tissues and cell lines were tested by qPCR. Effects of ANRIL silence on cell viability, migration and invasion, apoptosis, and miR-99a expression in MKN-45 and SGC-7901 cells were measured using CCK-8, Transwell assay, flow cytometry, and qPCR assays, respectively. Then, effects of miR-99a inhibition on ANRIL-silenced cells were evaluated. B-lymphoma Mo-MLV insertion... Tipo: Info:eu-repo/semantics/article Palavras-chave: Gastric cancer; LncRNA ANRIL; MiR-99a; BMI1; Apoptotic pathway; Notch/mTOR pathway. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001000609 Registros recuperados: 2 Primeira ... 1 ... Última

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