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Effects of cholestyramine and lovastatin upon plasma lipids and egg yolk cholesterol levels of laying hens Braz. J. Vet. Res. Anim. Sci.
MORI,Agnes Veridiana; MENDONÇA Jr.,Cássio Xavier de; WATANABE,Claudio.
The purpose of this study was to evaluate the effect of cholestyramine and lovastatin, lipid-lowering agents, upon egg quality, reproductive performance, plasma lipids and egg yolk cholesterol levels of Shaver laying hens. Twenty-six-weeks-old hens were fed basal diet without animal products containing 0.2% cholestyramine (COL1), 0.3% cholestyramine (COL2) or 0.005% lovastatin (LOV) for 6 weeks. It was observed that the supplementation of the drugs did not impair albumen and shell quality. Hen performance was not adversely affected, with the exception of the significant reduction (p < 0.05) in egg weights. No significant changes were observed on plasma lipids, and egg yolk cholesterol remained unchanged with the addition of the drugs.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cholesterol; Cholestyramine; Lovastatin; Egg Yolk; Chickens.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95962000000100015
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Production of angkak through co-culture of Monascus purpureus and Monascus ruber BJM
Panda,Bibhu Prasad; Javed,Saleem; Ali,Mohd.
Angkak (red mold rice, red yeast rice, Chinese red rice) is a traditional Chinese medicine produced by solid-state fermentation of cooked non-glutinous rice with Monascus species. The secondary metabolite of Monascus species, monacolin K /lovastatin, has been proven to lower blood lipid levels. In this study, a co-culture of Monascus purpureus MTCC 369 and Monascus ruber MTCC 1880 was used for angkak production. Four medium parameters screened by Plackett-Burman design were optimized by response surface methodology for highest lovastatin production in angkak during solid-state fermentation by the co-culture. Maximum lovastatin production of 2.84 mg g-1 was predicted in solid medium containing 20 g rice and 40 ml liquid nutrients medium (malt extract 9.68 g...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Angkak. Co-culture; Monascus purpureus; Monascus ruber; Lovastatin; Response surface methodology.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000300028
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Response surface methodology for optimization of production of lovastatin by solid state fermentation BJM
Pansuriya,Ruchir C.; Singhal,Rekha S..
Lovastatin, an inhibitor of HMG-CoA reductase, was produced by solid state fermentation (SSF) using a strain of Aspergillus terreus UV 1718. Different solid substrates and various combinations thereof were evaluated for lovastatin production. Wheat bran supported the maximum production (1458 ± 46 µg g-1 DFM) of lovastatin. Response surface methodology (RSM) was applied to optimize the medium constituents. A 2(4) full-factorial central composite design (CCD) was chosen to explain the combined effects of the four medium constituents, viz. moisture content, particle size of the substrate, di-potassium hydrogen phosphate and trace ion solution concentration. Maximum lovastatin production of 2969 µg g-1 DFM was predicted by the quadratic model which was...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lovastatin; Response surface methodology; Solid state fermentation; Aspergillus terreus.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000100024
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