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| Chaves-Moreira,Daniele; Senff-Ribeiro,Andrea; Wille,Ana Carolina Martins; Gremski,Luiza Helena; Chaim,Olga Meiri; Veiga,Silvio Sanches. |
| Abstract Brown spiders are venomous arthropods that use their venom for predation and defense. In humans, bites of these animals provoke injuries including dermonecrosis with gravitational spread of lesions, hematological abnormalities and impaired renal function. The signs and symptoms observed following a brown spider bite are called loxoscelism. Brown spider venom is a complex mixture of toxins enriched in low molecular mass proteins (4–40 kDa). Characterization of the venom confirmed the presence of three highly expressed protein classes: phospholipases D, metalloproteases (astacins) and insecticidal peptides (knottins). Recently, toxins with low levels of expression have also been found in Loxosceles venom, such as serine proteases, protease... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Brown spider; Loxosceles; Venom; Toxins; Loxoscelism; Phospholipase-D; Metalloprotease; Insecticidal peptides; Serineprotease; Hyaluronidase. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992017000100201 |
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| Yigit,N.; Bayram,A.; Ulasoglu,D.; Danisman,T.; Corak Ocal,I.; Sancak,Z.. |
| Loxoscelism is caused by envenomation by spiders that belong to the Loxosceles genus. In loxoscelism, a local necrotic lesion appears and, in many cases, loxoscelism or necrotic araneism is considered a serious public health problem. There is no diagnostic test available to help the physician make a diagnostic or therapeutic decision. Here, we report the case of a severe dermonecrotic araneism (loxoscelism) in Turkey probably due to the bite of Loxosceles rufescens. There was little erythema at the beginning, followed by severe necrosis after 20 days, and skin grafting was needed although the case was treated. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Spider bite; Loxoscelism; Skin grafting; Loxosceles rufescens; Turkey. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000100016 |
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| Pereira,NB; Kalapothakis,E; Vasconcelos,AC; Chatzaki,M; Campos,LP; Vieira,FO; Verçosa,BLA; Silva,SS; Ferreira,WM; Moro,L. |
| Envenomation by Loxosceles bites is characterized by dermonecrotic and/or systemic features that lead to several clinical signs and symptoms called loxoscelism. Dermonecrotic lesions are preceded by thrombosis of the dermal plexus. Recent studies show that atheromatous plaque is prone to thrombosis due to endothelial cell apoptosis. To the best of our knowledge, there are no reports of microscopic dermal lesion and endothelial cell apoptosis induced by Loxosceles similis venom in the literature. Thus, the aim of the present study is to describe histological lesions induced by L. similis venom in rabbit skin and to elucidate whether apoptosis of endothelial cells is involved in the pathogenesis of loxoscelism. Forty male rabbits were split into two groups:... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Loxosceles similis; Loxoscelism; Dermonecrosis; Cutaneous loxoscelism; Apoptosis. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992012000300005 |
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| Ramires,E. N.; Retzlaff,A. V. L.; Deconto,L. R.; Fontana,J. D.; Marques,F. A.; Marques-da-Silva,E.. |
| Some venomous spiders of the genus Loxosceles can reach high population densities inside and around houses. In Brazil, most spider accidents are related to Loxosceles intermedia. Control of loxoscelism should utilize integrated pest management tools, such as vacuum cleaners, to eliminate egg sacs, webs and spiders. The present study tested the efficacy of one type of vacuum cleaner (for professional and domestic use) in the control of L. intermedia populations. Cockroaches (Pycnoscelus surinamensis) were used in some tests for comparison. Vacuuming using standard accessories or a paper tube resulted in the death of all female (n=60), male (n=60), young (n=60) and just-hatched (n=60) L. intermedia, and all egg sacs (n=5) were destroyed. The removal of the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Loxoscelism; Loxosceles intermedia; Vacuum cleaners; Venomous animals; Spiders. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000300005 |
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| ALMEIDA,Marlus Q.; SALVATIERRA,Lidianne; CARVALHO,Thiago G.; PRESTES,Francisco J.; BRESCOVIT,Antonio D.; GASNIER,Thierry R.. |
| ABSTRACT Spiders of the genus Loxosceles, commonly known as brown recluse spiders, can cause serious accidents in humans. Their venom has a powerful proteolytic and hemolytic action. Each year these spiders are the cause of a great number of araneism in Brazil. This work presents new records of Loxosceles amazonica for the municipal districts of Manaus and Iranduba, Amazonas, Brazil. |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Brown recluse spiders; Venomous spider; Loxoscelism; Distribution. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672017000200163 |
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| Barretto,O.C. de O.; Satake,M.; Nonoyama,K.; Cardoso,J.L.C.. |
| Eighty micrograms red blood cell (RBC) ghosts from patients who had previously exhibited the cutaneous form of loxoscelism (presenting localized dermonecrosis) and the viscerocutaneous form of loxoscelism (presenting dermonecrosis, hemoglobinuria, hematuria, and jaundice) and from controls were incubated with 2.5 µg crude Loxosceles gaucho venom in 5 mM phosphate buffer, pH 7.4, at 37ºC. Among all membrane proteins, quantitative proteolysis of the important integral transmembrane protein 3 increased with venom dose and with incubation time from 30 to 120 min, as demonstrated by gel densitometry. Similar quantitative data were obtained for RBC ghosts from patients and from control subjects, a fact that argues against the possibility of genetic factors... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Loxoscelism; Loxosceles sp; Spider venom; Red blood cell membrane protein 3. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000300004 |
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