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Iron homeostasis in the lung Biol. Res.
GHIO,ANDREW J; TURI,JENNIFER L; YANG,FUNMEI; GARRICK,LAURA M; GARRICK,MICHAEL D.
Iron is essential for many aspects of cellular function. However, it also can generate oxygen-based free radicals that result in injury to biological molecules. For this reason, iron acquisition and distribution are tightly regulated. Constant exposure to the atmosphere results in significant exposure of the lungs to catalytically active iron. The lungs have a mechanism for detoxification to prevent associated generation of oxidative stress. Those same proteins that participate in iron uptake in the gut are also employed in the lung to transport iron intracellularly and sequester it in an inactive form within ferritin. The release of metal is expedited (as transferrin and ferritin) from lung tissue to the respiratory lining fluid for clearance by the...
Tipo: Journal article Palavras-chave: Lung diseases; Oxidative stress; SLC11A2 protein; SLC40A1 protein.
Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000100008
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Varicella pneumonia in immunocompetent adults: report of two cases, with emphasis on high-resolution computed tomography findings BJID
Gasparetto,Emerson L.; Warszawiak,Danny; Tazoniero,Priscilla; Escuissato,Dante L.; Marchiori,Edson.
We report two cases of varicella pneumonia in immunocompetent patients, with emphasis on high-resolution computer tomography manifestations. The predominant findings consisted of multiple bilateral nodules, ranging from 1-10 mm in diameter, with or without a surrounding halo of ground-glass attenuation. Other findings include ground-glass opacities, focal areas of consolidation and small pleural effusions.
Tipo: Info:eu-repo/semantics/report Palavras-chave: Lung diseases; Lung infection; Computed tomography; High-resolution computed tomography.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000300010
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