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	Provedor de dados BJMBR (1) BJPS (1) Autor Ayata,Neşe (1) Bucak,Seyda (1) Chen,M.M. (1) Du,Y.Q. (1) Fan,J.G. (1) Hu,Y. (1) Sezer,Ali Demir (1) Turanlı,Eda Tahir (1) Wang,Y.Q. (1) Xu,L.M. (1) Yan,S.Y. (1) Mais... Palavra-chave Magnetic nanoparticles (2) Cell culture (1) Drug delivery (1) Fe2O3 (1) Hepatocarcinoma cells (1) Liver cancer (1) Magnetic fluid hyperthermia (1) Monoclonal antibody (1) Ranibizumab (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2020 (1) 2014 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Therapeutic mechanism of treating SMMC-7721 liver cancer cells with magnetic fluid hyperthermia using Fe2O3 nanoparticles BJMBR Yan,S.Y.; Chen,M.M.; Fan,J.G.; Wang,Y.Q.; Du,Y.Q.; Hu,Y.; Xu,L.M.. This study aimed to investigate the therapeutic mechanism of treating SMMC-7721 liver cancer cells with magnetic fluid hyperthermia (MFH) using Fe2O3 nanoparticles. Hepatocarcinoma SMMC-7721 cells cultured in vitro were treated with ferrofluid containing Fe2O3 nanoparticles and irradiated with an alternating radio frequency magnetic field. The influence of the treatment on the cells was examined by inverted microscopy, MTT and flow cytometry. To study the therapeutic mechanism of the Fe2O3 MFH, Hsp70, Bax, Bcl-2 and p53 were detected by immunocytochemistry and reverse transcription polymerase chain reaction (RT-PCR). It was shown that Fe2O3 MFH could cause cellular necrosis, induce cellular apoptosis, and significantly inhibit cellular growth, all of which... Tipo: Info:eu-repo/semantics/article Palavras-chave: Fe2O3; Magnetic nanoparticles; Magnetic fluid hyperthermia; Hepatocarcinoma cells; Liver cancer. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014001100947 Preparation and in vitro characterization of monoclonal antibody ranibizumab conjugated magnetic nanoparticles for ocular drug delivery BJPS Ayata,Neşe; Sezer,Ali Demir; Bucak,Seyda; Turanlı,Eda Tahir. Gold coated magnetite nanoparticles were prepared and coated with ranibizumab as an ocular drug delivery system. The surface morphologies of the nanoparticles were determined by Scanning Electron Microscopy (SEM). The size and surface charge were determined by using the dynamic light scattering (DLS) technique. Crystallographic properties of the gold coated Fe3O4 nanoparticles were recorded on X-ray diffractometer (XRD) the XRD pattern of nanoparticlees were shown to have uniqe Fe3O4 and gold peaks. Conjugation of ranibizumab onto nanoparticles was achieved using the physical adsorption method. The amount of ranibizumab on the surface of the nanoparticles was determined by thermogravimetric analysis (TGA). In the in vitro release studies performed using UV... Tipo: Info:eu-repo/semantics/article Palavras-chave: Ranibizumab; Monoclonal antibody; Drug delivery; Magnetic nanoparticles; Cell culture. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100587 Registros recuperados: 2 Primeira ... 1 ... Última

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