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DIFFERENCES AND SIMILARITIES BETWEEN Anaplasma marginale and Anaplasma phagocytophylum Rev Salud Anim.
Corona,Belkis; Martínez,Siomara.
Anaplasma marginale and A. phagocytophilum are intracellularrickettsial pathogens causing bovine anaplasmosis and human granulocyticanaplasmosis, respectively. Effective vaccines for the control ofanaplasmosis are not available despite attempts using differentapproaches, such as attenuated strains, infected erythrocyteand tick cell-derived purified antigens. Recent reports demonstrated that A. marginale and A. phagocytophilum co-exist in geographic areas, that concurrent infections may occur in ruminants and ticks and that there are similarities and differences at molecular level between both species. The aim of this article is to make a comparison between the main characteristics of Anaplasma marginale and Anaplasma phagocytophilum.
Tipo: Journal article Palavras-chave: Anaplasma marginale; Anaplasma phagocytophilum; Major surface proteins.
Ano: 2009 URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0253-570X2009000100001
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Characterization of recombinant MSP5 Anaplasma marginale Havana isolate BJM
Corona,B.; Machado,H.; Rodríguez,M.; Martínez,S..
Anaplasma marginale is the causative agent of bovine anaplasmosis, a disease of worldwide economic importance. Major surface proteins (MSPs) are involved in host-pathogen and tick-pathogen interactions and they have been used as markers for the genetic characterization of A. marginale strains and phylogenetic studies. The major surface protein 5 (MSP5) is highly conserved in the genus Anaplasma and in all isolates of A. marginale. The aim of the present work was to carry out the cloning, sequencing and characterization of the recombinant MSP5 Anaplasma marginale Havana isolate. The sequence of the msp5 gene of Anaplasma marginale Havana isolate with a size of 633 pb was determined (Acc. No. AY527217). This gene was cloned into pRSETB vector and expressed...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anaplasma marginale; Major surface proteins; Characterization; Havana isolate; HMSP5.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000400032
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