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Chioca,Lea Rosa; Müller,Juliane Centeno; Boareto,Ana Cláudia; Andreatini,Roberto; Dalsenter,Paulo Roberto. |
The aim of the present study was to evaluate the effects of sodium fluoride (NaF) on the male reproductive system. Adult male rats were exposed to NaF in drinking water for 30 days at three concentrations: 1.54 (control, tap water), 50 and 100 ppm. Body and organ weights, daily sperm production, sperm number and morphology were investigated. No difference was observed on the sperm number and morphology among the groups, as well as body weight and organ absolute and relative weights. Overall, despite the presence of a mild degree of dental fluorosis in the higher dose group, the results indicated that exposure to NaF at the doses used in the present study did not adversely affect sperm production and morphology of male rats. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fluoride; Sodium fluoride; Male rats; Reproductive toxicology; Dental fluorosis; Sperm. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000200011 |
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Boemler Hollenbach,Clarissa; Bortolini,Carlos Eduardo; Mattos Rodrigues,Juliano; Hirtz,Lucas; Bastos de Mello,Fernanda; Braga de Mello,João Roberto. |
The present study evaluates the effects of two commercial phytotherapic formulations containing Glycine max (L.) Merr. (Soy) (Phytotherapic A and Phytotherapic B) on Wistar rat fertility. Doses were based on the manufacturer's recommendation and increased in a logarithmic scale. The animals were divided into six experimental groups and a control group, which received distillated water. Three groups were treated with Phytotherapic A and three groups were treated with Phytotherapic B. The doses were: 4.3mg.kg-1.day-1, 21.5 mg.kg-1.day-1 and 43 mg.kg-1.day-1, respectively, for GPA1, GPA2, GPA3, and GPB1, GPB2, GPB3. The males were treated during ninety-one days, before and during the mating. Female Wistar rats were treated before and during the mating,... |
Tipo: Journal article |
Palavras-chave: Soy; Glycine max; Phytotherapic; Male rats; Fertility; Toxicity. |
Ano: 2012 |
URL: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0253-570X2012000100005 |
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