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	Provedor de dados BJMBR (1) Autor Camolezi,F.L. (1) Ciancaglini,P. (1) Millán,J.L. (1) Pizauro,J.M. (1) Simão,A.M.S. (1) Palavra-chave Alkaline phosphatase (1) Calcification (1) Ectopic mineralization (1) Endochondral ossification (1) Matrix vesicles (1) Osseous plate (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2006 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Contribution of matrix vesicles and alkaline phosphatase to ectopic bone formation BJMBR Ciancaglini,P.; Simão,A.M.S.; Camolezi,F.L.; Millán,J.L.; Pizauro,J.M.. Endochondral calcification involves the participation of matrix vesicles (MVs), but it remains unclear whether calcification ectopically induced by implants of demineralized bone matrix also proceeds via MVs. Ectopic bone formation was induced by implanting rat demineralized diaphyseal bone matrix into the dorsal subcutaneous tissue of Wistar rats and was examined histologically and biochemically. Budding of MVs from chondrocytes was observed to serve as nucleation sites for mineralization during induced ectopic osteogenesis, presenting a diameter with Gaussian distribution with a median of 306 ± 103 nm. While the role of tissue-nonspecific alkaline phosphatase (TNAP) during mineralization involves hydrolysis of inorganic pyrophosphate (PPi), it is unclear... Tipo: Info:eu-repo/semantics/article Palavras-chave: Matrix vesicles; Endochondral ossification; Osseous plate; Alkaline phosphatase; Ectopic mineralization; Calcification. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000500006 Registros recuperados: 1 Primeira ... 1 ... Última

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