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	Provedor de dados BABT (1) BJMBR (1) Autor Alishahi,Mojtaba (1) Farasat,Massoumeh (1) Jahangiri,Alireza (1) Li,Zhou (1) Liu,Ying (1) Mousavi,Hamideh (1) Namjooyan,Foroogh (1) Song,Zhiqi (1) Wang,Yupeng (1) Zhao,Guangming (1) Zhou,Wenhui (1) Mais... Palavra-chave Melanogenesis (2) Algae (1) Metabotropic glutamate receptor-4 (1) Mushroom tyrosinase (1) Persian Gulf (1) Th17 (1) Vitiligo (1) Zebrafish (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2020 (1) 2019 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última The Anti-melanogenesis Activities of Some Selected Brown Macroalgae from Northern Coasts of the Persian Gulf BABT Namjooyan,Foroogh; Farasat,Massoumeh; Alishahi,Mojtaba; Jahangiri,Alireza; Mousavi,Hamideh. Abstract Melanogenesis is a biological process which led to the synthesis of melanin pigment. Abnormal melanin production results in melasma, solar lentigo, post inflammatory melanoderma, etc. In this study, we examined the potential inhibitory effects of 17 brown macroalgae from Persian Gulf on melanogenesis. The effects of various concentrations (100, 250 and 500 µg/mL) of methanolic extracts of macroalgae belonging to four genera (including: Padina, Colpomonia, Cystoseira and Sargassum) were studied on oxidation of L-Dopa by mushroom tyrosinase. Subsequently, the activity of macroalgae with high inhibitory effect on monophenolase activity of mushroom tyrosinase and zebrafish was investigated using L-tyrosine as a substrate. Anti-melanogenesis effects of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Algae; Persian Gulf; Melanogenesis; Mushroom tyrosinase; Zebrafish. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132019000100301 Critical role of metabotropic glutamate receptor 4 in bone marrow-derived dendritic cells in the Th17 cell differentiation and the melanogenesis of B16 cells BJMBR Zhao,Guangming; Zhou,Wenhui; Liu,Ying; Wang,Yupeng; Li,Zhou; Song,Zhiqi. Vitiligo is an acquired pigmentary disorder resulting from selective destruction of melanocytes. Emerging studies have suggested that T helper cell 17 (Th17) is potentially implicated in vitiligo development and progression. It was recently discovered that metabotropic glutamate receptor 4 (mGluR4) can modulate Th17-mediated adaptive immunity. However, the influence of mGluR4 on melanogenesis of melanocytes has yet to be elucidated. In the present study, we primarily cultured mouse bone marrow-derived dendritic cells (BMDC) and then knocked down and over-expressed mGluR4 using transfection. Transduced BMDC were co-cultured with CD4+ T cells and the expression of Th17-related cytokines were measured. The morphology and melanogenesis of B16 cells were... Tipo: Info:eu-repo/semantics/article Palavras-chave: Metabotropic glutamate receptor-4; Th17; Melanogenesis; Vitiligo. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000400604 Registros recuperados: 2 Primeira ... 1 ... Última

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