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Molecular and cellular mechanisms for the regulation of ovarian follicular function in cows OAK
SHIMIZU, Takashi; 清水, 隆.
Ovary is an important organ that houses the oocytes (reproductive cell). Oocyte growth depends on the function of follicular cells such as the granulosa and theca cells. Two-cell two gonadotropin systems are associated with oocyte growth and follicular cell functions. In addition to these systems, it is also known that several growth factors regulate oocyte growth and follicular cell functions. Vascular endothelial growth factor (VEGF) is involved in thecal vasculature during follicular development and the suppression of granulosa cell apoptosis. Metabolic factors such as insulin, growth hormone (GH) and insulin-like growth factor 1 (IGF-1) also play critical roles in the process of follicular development and growth. These factors are associated not only...
Palavras-chave: Endotoxin; Metabolic factors; Ovarian follicle; Steroid hormone; Vascular endothelial growth factor (VEGF).
Ano: 2016 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4325
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