|
|
|
|
|
| BOKOWSKI,LIANE V.V.; SOBRINHO,ROBERTO B.; ARMIJO,CRISTIÁN J.V.; DANI,CAROLINE; HENRIQUES,JOÃO A.P.; FUNCHAL,CLÁUDIA. |
| ABSTRACT Vitis labrusca L. is the main species used for wine and juice production in Brazil. The grapevine leaves can be used both as functional foods and as cheapest sources for the extraction of phenolic compounds. Besides the antioxidant activity, grapevine leaves exhibited significant anti-inflammatory activity. Therefore, the aim of this study was to develop and validate an analytical methodology to determine the metals selenium (96Se), chromium (53Cr), nickel (62Ni), cadmium (111Cd) and lead (206Pb) in 30 samples of grapevine leaf extracts (Vitis labrusca, Bordo cultivar) using inductively coupled plasma mass spectrometry (ICP-MS). To obtain the grapevine leaf extracts the samples were milled, weighed and digested in microwave oven with nitric acid.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: ICP-MS; Metals; Method validation; Vitis labrusca L. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000602247 |
| |
|
| |
|
|
| Pandey,Saurabh; Pandey,Preeti; Kumar,Raj; Singh,Narendra Pal. |
| Residual solvents in pharmaceutical samples are monitored using gas chromatography with head space. Based on good manufacturing practices, measuring residual solvents is mandatory for the release testing of all active pharmaceutical ingredients (API). The analysis of residual organic solvents (methanol, acetone, cyclohexane, dichloromethane, toluene) in Omeprazole, an active pharmaceutical ingredient was investigated. Omeprazole is a potent reversible inhibitor of the gastric proton pump H+/K+-ATPase. The Head space gas chromatography (HSGC) method described in this investigation utilized a SPB TM-624, Supelco, 30 m long x 0.25 mm internal diameter, 1.4µm-thick column. Since Omeprazole is a thermally labile compound, the selection of the proper injector... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Headspace-gas chromatography; Omeprazole; Method validation; Residual solvents release testing. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000200019 |
| |
|
|
| NÁTHIA-NEVES,Grazielle; NOGUEIRA,Gislaine Chystina; VARDANEGA,Renata; MEIRELES,Maria Angela de Almeida. |
| Abstract In this work, it was developed a fast, simple and selective method for quantification of genipin and geniposide from unripe fruits of genipap, which are known as natural colorants, blue and yellow, respectively. The compounds separation was performed in a fused-core C18 column using as mobile phase water (A) and acetonitrile (B) both acidified with 0.1% formic acid, with the following gradient: 0 min, 99% A; 9 min, 75% A; 10 min, 99% A and 13 min, 99% A. The temperature and flow rate that allowed the best chromatographic performance were 35 °C and 1.5 mL/min, respectively, resulting a total run time of 13 min, including column clean-up and re-equilibration. This short analysis time represents an advantage compared to the methods reported in the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Blue natural colorant; Method validation; Iridoids. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612018000500116 |
| |
|
| |
|
|
|
