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	Provedor de dados 56 (1) Autor Ji,Yu Zu (1) Jing,Meng (1) Ke,Qi (1) Wang,An-qun (1) Xie,Gang (1) Zou,li-li (1) Mais... Palavra-chave Apoptosis (1) FGFR1 (1) Gastric cancer (1) MiR-497 (1) Post-transcriptional (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2019 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última FGFR1 is an independent prognostic factor and can be regulated by miR-497 in gastric cancer progression 56 Xie,Gang; Ke,Qi; Ji,Yu Zu; Wang,An-qun; Jing,Meng; Zou,li-li. Fibroblast growth factor receptor 1 (FGFR1) has been reported in gastric cancer to be a prognostic factor. However, miR-497-targeted FGFR1 has not been explored in the carcinogenesis of gastric cancer. The present study intended to revalidate the prognostic significance of FGFR1 in patients with gastric cancer, and the mechanism of miR-497-regulated FGFR1 was investigated in gastric cancer cell proliferation and apoptosis. The messenger RNA (mRNA) and protein levels were assayed by RT-qPCR and western blotting, respectively. The targeted genes were predicted by a bioinformatics algorithm and confirmed by a dual luciferase reporter assay. Cell proliferation was analyzed by CCK-8 assay. Annexin V-FITC/PI staining was used to evaluate the apoptosis in AGS and... Tipo: Info:eu-repo/semantics/article Palavras-chave: FGFR1; MiR-497; Apoptosis; Post-transcriptional; Gastric cancer. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000100602 Registros recuperados: 1 Primeira ... 1 ... Última

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