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	Provedor de dados BJMBR (3) Boletín de la Sociedad (1) BJPS (1) Autor Viana,M.B. (2) Zangrossi Jr.,H. (2) Abbaszadeh,Mehran (1) Albertó,Edgardo (1) Bueno,C.H. (1) Callera,J.C. (1) Colombari,E. (1) De Luca Jr.,L.A. (1) Kiani,Farhoush (1) Koohyar,Fardad (1) Lechner,Bernardo E. (1) Menani,J.V. (1) Nascimento,J.O.G. (1) Pousti,Mohammad (1) Mais... Palavra-chave Muscimol (5) Elevated T-maze (2) Generalized anxiety disorder (2) Panic disorder (2) Acid/dissociation constants (1) Amanita (1) Amygdala (1) Awake rats (1) Bezold-Jarisch reflex (1) Computational chemistry (1) Density Functional Theory (1) Dorsomedial hypothalamus (1) GABA receptors (1) Light/dark transition test in the rat (1) Nanodrug (1) Nucleus tractus solitarius (1) Parasympathetic component (1) Rabdomiolisis (1) Tricholoma equestre (1) Ácido iboténico (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Info:eu-repo/semantics/other (2) Ano 2015 (1) 2010 (1) 2008 (1) 2005 (2) País Brazil (4) Argentina (1) Idioma Inglês (4) Espanhol (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 5 Primeira ... 1 ... Última Especies tóxicas de Agaricales halladas en la Argentina: nueva cita de Amanita pantherina y reevaluación de la comestibilidad de Tricholoma equestre Boletín de la Sociedad Lechner,Bernardo E.; Albertó,Edgardo. Si bien los hongos comestibles en la Argentina no constituyen una parte importante de la dieta, algunas personas colectan y consumen especies silvestres. Esto ha ocasionado en los últimos años la intoxicación de un número importante de adultos y niños. En el presente trabajo se cita por primera vez para la Argentina el hongo tóxico Amanita pantherina, se describen las colecciones halladas y se provee una clave para la determinación de las especies de Amanita Secc. Amanita. A su vez se describe y se reevalúa la comestibilidad de Tricholoma equestre causante de un nuevo síndrome de intoxicación, por lo cual fue recientemente prohibido en varios países de la comunidad Europea. Tipo: Info:eu-repo/semantics/article Palavras-chave: Amanita; Ácido iboténico; Muscimol; Rabdomiolisis; Tricholoma equestre. Ano: 2008 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-23722008000200006 Effects of reversible inactivation of the dorsomedial hypothalamus on panic- and anxiety-related responses in rats BJMBR Nascimento,J.O.G.; Zangrossi Jr.,H.; Viana,M.B.. The medial hypothalamus is part of a neurobiological substrate controlling defensive behavior. It has been shown that a hypothalamic nucleus, the dorsomedial hypothalamus (DMH), is involved in the regulation of escape, a defensive behavior related to panic attacks. The role played by the DMH in the organization of conditioned fear responses, however, is less clear. In the present study, we investigated the effects of reversible inactivation of the DMH with the GABA A agonist muscimol on inhibitory avoidance acquisition and escape expression by male Wistar rats (approximately 280 g in weight) tested in the elevated T-maze (ETM). In the ETM, inhibitory avoidance, a conditioned defensive response, has been associated with generalized anxiety disorder. Results... Tipo: Info:eu-repo/semantics/other Palavras-chave: Muscimol; Generalized anxiety disorder; Panic disorder; Dorsomedial hypothalamus; Elevated T-maze. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000900009 The bradycardic and hypotensive responses to serotonin are reduced by activation of GABA A receptors in the nucleus tractus solitarius of awake rats BJMBR Callera,J.C.; Colombari,E.; De Luca Jr.,L.A.; Menani,J.V.. We investigated the effects of bilateral injections of the GABA receptor agonists muscimol (GABA A) and baclofen (GABA B) into the nucleus tractus solitarius (NTS) on the bradycardia and hypotension induced by iv serotonin injections (5-HT, 2 µg/rat) in awake male Holtzman rats. 5-HT was injected in rats with stainless steel cannulas implanted bilaterally in the NTS, before and 5, 15, and 60 min after bilateral injections of muscimol or baclofen into the NTS. The responses to 5-HT were tested before and after the injection of atropine methyl bromide. Muscimol (50 pmol/50 nl, N = 8) into the NTS increased basal mean arterial pressure (MAP) from 115 ± 4 to 144 ± 6 mmHg, did not change basal heart rate (HR) and reduced the bradycardia (-40 ± 14 and -73 ± 26... Tipo: Info:eu-repo/semantics/article Palavras-chave: Muscimol; GABA receptors; Nucleus tractus solitarius; Parasympathetic component; Bezold-Jarisch reflex; Awake rats. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700016 The inactivation of the basolateral nucleus of the rat amygdala has an anxiolytic effect in the elevated T-maze and light/dark transition tests BJMBR Bueno,C.H.; Zangrossi Jr.,H.; Viana,M.B.. Pharmacological evidence indicates that the basolateral nucleus of the amygdala (BLA) is involved in the mediation of inhibitory avoidance but not of escape behavior in the elevated T-maze test. These defensive responses have been associated with generalized anxiety disorder (GAD) and panic disorder, respectively. In the present study, we determined whether the BLA plays a differential role in the control of inhibitory avoidance and escape responses in the elevated T-maze. Male Wistar rats (250-280 g, N = 9-10 in each treatment group) were pre-exposed to one of the open arms of the maze for 30 min and 24 h later tested in the model after inactivation of the BLA by a local injection of the GABA A receptor agonist muscimol (8 nmol in 0.2 µL). It has been... Tipo: Info:eu-repo/semantics/other Palavras-chave: Muscimol; Generalized anxiety disorder; Panic disorder; Amygdala; Elevated T-maze; Light/dark transition test in the rat. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005001100019 Theoretically nanoscale study on ionization of muscimol nano drug in aqueous solution BJPS Kiani,Farhoush; Abbaszadeh,Mehran; Pousti,Mohammad; Koohyar,Fardad. In the present work, acid dissociation constant (pKa) values of muscimol derivatives were calculated using the Density Functional Theory (DFT) method. In this regard, free energy values of neutral, protonated and deprotonated species of muscimol were calculated in water at the B3LYP/6-31G(d) basis sets. The hydrogen bond formation of all species had been analyzed using the Tomasi's method. It was revealed that the theoretically calculated pKa values were in a good agreement with the existing experimental pKa values, which were determined from capillary electrophoresis, potentiometric titration and UV-visible spectrophotometric measurements. Tipo: Info:eu-repo/semantics/article Palavras-chave: Nanodrug; Muscimol; Acid/dissociation constants; Computational chemistry; Density Functional Theory. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000100213 Registros recuperados: 5 Primeira ... 1 ... Última

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