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| SILVA,Emily Marcele Soares; SILVA,Ingrid Reis da; OGUSKU,Mauricio Morishi; CARVALHO,Clarice Maia; MAKI,Cristina Sayuri; PROCÓPIO,Rudi Emerson de Lima. |
| ABSTRACT Tuberculosis (TB) remains one of the most deadly communicable infectious diseases, causing 1.4 million deaths in 2015 worldwide due to many conditions, including the inadequate treatment and the emergence of multidrug-resistant strains of the causal agent, Mycobacterium tuberculosis. Therefore, drugs developed from natural sources, as microorganisms and plant extracts, are a frequent target for the research and discovery of antimicrobial compounds. The current study started the characterization of compounds produced by an Aspergillus fumigatus isolated from copaíba (Copaifera multijuga) that efficiently inhibits M. tuberculosis by releasing the compounds into the fermentation broth under specific culture conditions. A preliminary assay was carried... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mycobacterium spp.; Antimicrobial activity; Copaíba; Chromatography. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672018000100063 |
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