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Transmission Electron Microscopy Studies of the Vestibulocochlear Nerve in Chronic Diabetic Rats International Journal of Morphology
Vasconcelos,Carlos Augusto Carvalho de; Fazan,Valéria Paula Sassoli; Moore,Kenneth Charles; Nessler,Randy Alan; Valença,Marcelo Moraes.
It is widely described in the literature that diabetic patients present hearing impairment. Despite the histological alterations of the internal ear structures in these patients as well as in experimental models of diabetes, to the best of our knowledge, an histological evaluation of the vestibulocochlear nerve have not been performed. In the present study, ultrastructural alterations are described and compared between a spinal nerves and a cranial nerve in rats with chronic induced diabetes. Male Wistar rats (n = 12), fed with standard diet from the animal care facility at 42 days of age were used. Induced diabetic animals (n=6) were fasted for 12 hours prior to being injected intraperitoneally with streptozotocin (STZ - 60mg/kg) in a single dose. Control...
Tipo: Journal article Palavras-chave: Experimental diabetes; Vestibulocochlear nerve; Ultrastructure; Myelinated fibers; Axonal atrophy.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000100045
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Hind Limb Sensory Innervation in Rats: Comparison between Sural and Saphenous Nerve Morphometry International Journal of Morphology
Neri,Letícia Oliveira; de Amorim,Milena Menezes; Campos,Stella Andrade Rodrigues; Sanada,Luciana Sayuri; Fazan,Valéria Paula Sassoli.
Although numerous studies investigate sensory recovery of the hind paw of the rat after nerve damage, still no comprehensive overview of its normal innervation is present in the literature. We investigated the morphometry of myelinated fibers in the sural and saphenous nerves and analyzed their size distributions in young rats. Six 30-day-old female Wistar rats were perfused with 2.5% glutaraldehyde and their right and left sural and saphenous nerves were prepared for light microscopy and morphometry. Morphometric data were compared between segments (proximal versus distal) and sides (right versus left) for the same nerves. Also, segments from right or left sides were compared between nerves (sural versus saphenous). Both, the sural and saphenous nerves,...
Tipo: Journal article Palavras-chave: Sural nerve; Saphenous nerve; Morphometry; Myelinated fibers.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000200052
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