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	Provedor de dados 56 (1) Autor Castellano,G. (1) Covolan,R.J.M. (1) Dias,C.S.B. (1) Foerster,B. (1) Li,L.M. (1) Palavra-chave Brain activation (1) Brain energy metabolism (1) Functional experiments (1) N-acetyl-L-aspartate (1) N-acetyl-aspartyl-glutamate (1) Proton magnetic resonance spectroscopy (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2012 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última NAA and NAAG variation in neuronal activation during visual stimulation 56 Castellano,G.; Dias,C.S.B.; Foerster,B.; Li,L.M.; Covolan,R.J.M.. N-acetyl-aspartyl-glutamate (NAAG) and its hydrolysis product N-acetyl-L-aspartate (NAA) are among the most important brain metabolites. NAA is a marker of neuron integrity and viability, while NAAG modulates glutamate release and may have a role in neuroprotection and synaptic plasticity. Investigating on a quantitative basis the role of these metabolites in brain metabolism in vivo by magnetic resonance spectroscopy (MRS) is a major challenge since the main signals of NAA and NAAG largely overlap. This is a preliminary study in which we evaluated NAA and NAAG changes during a visual stimulation experiment using functional MRS. The paradigm used consisted of a rest period (5 min and 20 s), followed by a stimulation period (10 min and 40 s) and another... Tipo: Info:eu-repo/semantics/article Palavras-chave: Proton magnetic resonance spectroscopy; Functional experiments; Brain activation; Brain energy metabolism; N-acetyl-L-aspartate; N-acetyl-aspartyl-glutamate. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012001100006 Registros recuperados: 1 Primeira ... 1 ... Última

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