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N-terminal prohormone brain natriuretic peptide (NT-proBNP) as a noninvasive marker for restrictive syndromes BJMBR
Mady,C.; Fernandes,F.; Ramires,F.J.A.; Nastari,L.; Buck,P.C.; Arteaga,E.; Ianni,B.M.; Salemi,V.M.C..
Constrictive pericarditis (CP) and restrictive cardiomyopathy share many similarities in both their clinical and hemodynamic characteristics and N-terminal prohormone brain natriuretic peptide (NT-proBNP) is a sensitive marker of cardiac diastolic dysfunction. The objectives of the present study were to determine whether serum NT-proBNP was high in patients with endomyocardial fibrosis (EMF) and CP, and to investigate how this relates to diastolic dysfunction. Thirty-three patients were divided into two groups: CP (16 patients) and EMF (17 patients). The control group consisted of 30 healthy individuals. Patients were evaluated by bidimensional echocardiography, with restriction syndrome evaluated by pulsed Doppler of the mitral flow and serum NT-proBNP...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Constrictive pericarditis; Endomyocardial fibrosis; NT-proBNP; Restrictive cardiomyopathy.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000800004
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N-terminal-pro-brain natriuretic peptide, but not brain natriuretic peptide, is increased in patients with severe obesity BJMBR
Fernandes,F.; Ramires,F.J.A.; Buck,P.C.; Almeida,I.J.; Rabelo,R.; Dantas,S.A.; Salemi,V.M.C.; Halpern,A.; Mady,C..
Elevated body mass index (BMI) has been reported as a risk factor for heart failure. Prevention of heart failure through identification and management of risk factors and preclinical phases of the disease is a priority. Levels of natriuretic peptides as well as activity of their receptors have been found altered in obese persons with some conflicting results. We investigated cardiac involvement in severely obese patients by determining N-terminal-pro-brain natriuretic peptide (NT-proBNP) and brain natriuretic peptide (BNP) and attempting to correlate the levels of these peptides in serum and plasma, respectively, with BMI, duration of obesity, waist circumference, and echocardiographic parameters. Thirty-three patients with severe obesity (mean BMI: 46.39...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Obesity; Heart failure; NT-proBNP; Brain natriuretic peptide.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000200001
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