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| SILVA, R. A. e; PIRAINE, R. E. A.; SANTOS JUNIOR, A. G. dos; CUNHA, R. C.; GONÇALVES, V. S.; SANTOS, F. D. S.; LEITE, F. P. L.. |
| Neospora caninum, parasito causador da neosporose, é conhecido mundialmente como um dos principais responsáveis por abortos em rebanhos bovinos, causando prejuízos econômicos à pecuária. As infecções e transmissões do parasito entre os animais são de difícil combate, assim, métodos de diagnóstico e controle devem ser aplicados para reduzir a disseminação do patógeno nas propriedades. A vacinação de rebanhos seria uma alternativa para o controle, contudo, a falta de uma vacina segura e eficaz impede a aplicação deste método de controle. O parasito possui importantes proteínas estruturais que auxiliam no processo de infecção como proteínas de superfície, proteínas dos micronemas, antígenos dos grânulos densos e proteínas das róptrias. Antígenos dessas... |
| Tipo: Documentos (INFOTECA-E) |
Palavras-chave: Imunógeno; Perspectiva; Look out; Vacina de DNA.; Vacina viva; Proteína de superfície; Proteína do micronema; Neosporose; Antígeno; Vacina; Aborto; Neospora Caninum.; Parasito de animal; Neosporosis; Antigens; Vaccines.. |
| Ano: 2017 |
URL: http://www.infoteca.cnptia.embrapa.br/infoteca/handle/doc/1077355 |
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| Leesombun, Arpron; Boonmasawai, Sookruetai; Nishikawa, Yoshifumi. |
| Neosporosis has a worldwide distribution and causes economic losses in farming, particularly by increasing the risk of abortion in cattle. This study investigated the effects of Thai piperaceae (Piper betle, P. nigrum, and P. sarmentosum) extracts on Neospora caninum infections in vitro and in vivo. In an in vitro parasite growth assay based on the green fluorescent protein (GFP) signal, P. betle was the most effective extract at inhibiting parasite growth in human foreskin fibroblast cells (IC50 of GFP-expressing N. caninum parasites, 22.1 mu g/ml). The P. betle extract, at 25 mu g per ml, inhibited parasite invasion into host cells. Furthermore, in two independent experiments, treating N. caninum-infected mice with the P. betle extract for 7 days... |
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Palavras-chave: Neospora caninum; Neosporosis; Piper betle; Piper nigrum; Piper sarmentosum; Ethanol extract. |
| Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4578 |
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| Nishikawa, Yoshifumi. |
| Neosporosis is caused by the intracellular protozoan parasite Neospora caninum. This major disease-causing pathogen is responsible for inducing abortion in cattle, and these adverse events occur sporadically all over the world, including Japan. Currently, there are no vaccines on the market against infection with N. caninum. Because live and attenuated vaccines against N. caninum have had safety and effectiveness issues, development of a next-generation vaccine is urgently required. To develop a vaccine against neosporosis, my laboratory has been focused on the following: 1) understanding the host immune responses against Neospora infection, 2) identifying vaccine antigens and 3) developing an effective antigen-delivery system. The research strategy taken... |
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Palavras-chave: Adjuvant; Cattle; Neospora caninum; Neosporosis; Vaccine. |
| Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4544 |
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| Dubey, J. P.. |
| Neospora caninum is a recently recognized protozoan parasite of animals. Until 1988, it was misdiagnosed as Toxoplasma gondii. Neospora caninum or Neospora-like parasites cause paralysis and death in dogs and neonatal mortality and abortion in cattle, sheep, goats and horses. Its life cycle is not known. Tachyzoites and tissue cysts are the only asexual stages known and the carnivorous definitive host is not known. Transplacental transmission is the only known natural route of infection. |
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Palavras-chave: Neospora caninum; Neosporosis; Tachyzoites; Tissue cysts; Paralysis; Abortion. |
| Ano: 1992 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/163 |
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| Camillo,G; Cadore,GC; Ferreira,MST; Braünig,P; Maciel,JF; Pivoto,FL; Sangioni,LA; Vogel,FSF. |
| Toxoplasma gondii and Neospora caninum are two intracellular apicomplexan protozoa with worldwide distribution, and are responsible for reproductive disorders in sheep and cattle. These protozoa may infect a wide variety of domestic and wild animals, including birds, and backyard chickens can be used as sentinels of their infection. Parasites investigation in backyard chickens may be useful for the evaluation of environmental contamination with oocysts, of the disease cycle, and of risk factors associated with public health. The aim of this study was establish the importance of backyard chickens as T. gondii and N. caninum hosts. A number of 137 serum samples were collected from chickens in 23 farms in Rio Grande do Sul State, Brazil, and tested for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Backyard chickens; Neosporosis; Public health; Toxoplasmosis. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2015000200263 |
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| LIMA,DÉBORA C.V. DE; MELO,RENATA P.B. DE; ANDRADE,MULLER R.; DE ALCÂNTARA,ADRIANNE M.; MAGALHÃES,FERNANDO JORGE R.; CARVALHO,JÉSSICA C.S.; SILVA,RENATO A. DA; COSTA,MATEUS M. DA; MOTA,RINALDO A.. |
| Abstract This study aimed to evaluate the frequency of Neospora caninum antibodies in rodents from the Island of Fernando de Noronha, Brazil, and to contribute to epidemiological data on neosporosis in this region. Blood samples were collected from 154 black-rats (Rattus rattus) and 12 rock-cavies (Kerodon rupestris). The search for anti-N. caninum antibodies was made using the NAT technique, with a cut-off of 1:20. The frequency of positive mice was 5.19% (8/154 - 1:20 titer) and all rock-cavies were negative. The low frequency of antibodies against N. caninum in rodents found in the Island shows the low contamination of the environment where these animals live. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Neosporosis; Wildlife animals; NAT; Rattus rattus; Kerodon rupestris. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000700868 |
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| Braz,B.M.A.; Valente,J.D.M.; Villalobos,E.M.C.; Lara,M.C.C.S.H.; Machado,C.A.L.; Barbosa,I.C.; Melo,V.S.P.; Stipp,D.T.; Barros-Filho,I.R.; Biondo,A.W.; Vieira,T.S.W.J.; Vieira,R.F.C.. |
| ABSTRACT Although goat dairy farms in Brazil may have a higher risk of infection by Neospora caninum than beef farms, risk factor evaluation on a representative population remains to be fully established in Brazil. Accordingly, this study aimed to establish the occurrence of anti-N. caninum antibodies and factors associated with exposure in 406 blood samples from five dairy and three beef goat farms in the state of Paraíba, northeastern Brazil. Anti-N. caninum antibodies were detected by indirect immunofluorescence assay (IFA), with samples considered positive when reacting with dilution ≥ 1:50. A total of 106/406 goats (26.11%; 95% CI: 21.96-30.72%) were seroreactive comprising 2/61 (3.28%), 10/45 (22.22%), 13/50 (26.00%), 17/51 (33.33%) to 29/46 (63.04%)... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: IFA; Neosporosis; Seroprevalence; Small ruminants. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000100147 |
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| Guerra,Joice Loures; Okano,Werner; Bogado,Alexey Leon Gomel; Nino,Beatriz de Souza Lima; Martins,Felippe Danyel Cardoso; Cardim,Sérgio Tosi; Barros,Luiz Daniel de; Garcia,João Luis. |
| ABSTRACT: The presence of anti-Neospora caninum antibodies in beef cattle slaughtered in the northern region of the state of Paraná, Brazil, was evaluated. A total of 401 blood samples were collected; 281 samples from the municipality of Rolândia and 120 from the municipality of Borrazópolis, between April 2015 and November 2016. Of the total samples, 289 were from females and 112 from males, aged one and a half to eight years. Indirect fluorescent antibody test (IFAT) was performed, using a cut-off of 1:100. Variables were tabulated for statistical analyses (Fisher’s exact test and chi-square tests, p≤0.05). The analysis showed that of the 401 samples, 37 were positive for N. caninum, indicating a prevalence of 9.2 %, and observed titers were 1:100 (16),... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Neosporosis; Seroprevalence; IFAT; Cattle; Paraná state. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000500500 |
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