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	Provedor de dados BJMBR (1) Autor Aguiar Junior,A.C. (1) Capelozzi,V.L. (1) Espinoza,J.D. (1) Parra,E.R. (1) Silva,L.O. (1) Souza,H.S.P. (1) Mais... Palavra-chave Cytokines (1) Morphometry (1) Nitric oxide synthase isoforms (1) Pulmonary function tests and survival (1) Systemic sclerosis (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2013 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Morphometric evaluation of nitric oxide synthase isoforms and their cytokine regulators predict pulmonary dysfunction and survival in systemic sclerosis BJMBR Parra,E.R.; Aguiar Junior,A.C.; Silva,L.O.; Souza,H.S.P.; Espinoza,J.D.; Capelozzi,V.L.. Because histopathological changes in the lungs of patients with systemic sclerosis (SSc) are consistent with alveolar and vessel cell damage, we presume that this interaction can be characterized by analyzing the expression of proteins regulating nitric oxide (NO) and plasminogen activator inhibitor-1 (PAI-1) synthesis. To validate the importance of alveolar-vascular interactions and to explore the quantitative relationship between these factors and other clinical data, we studied these markers in 23 cases of SSc nonspecific interstitial pneumonia (SSc-NSIP). We used immunohistochemistry and morphometry to evaluate the amount of cells in alveolar septa and vessels staining for NO synthase (NOS) and PAI-1, and the outcomes of our study were cellular and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Systemic sclerosis; Nitric oxide synthase isoforms; Cytokines; Morphometry; Pulmonary function tests and survival. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001000881 Registros recuperados: 1 Primeira ... 1 ... Última

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