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	Provedor de dados BJMBR (2) Autor Aguiar,J.F. (1) Baptista,V. (1) Callera,J.C. (1) Colombari,E. (1) De Luca Jr.,L.A. (1) Menani,J.V. (1) Ogawa,W.N. (1) Varanda,W.A. (1) Mais... Palavra-chave Nucleus tractus solitarius (2) Awake rats (1) Bezold-Jarisch reflex (1) Electrophysiology (1) GABA receptors (1) Muscimol (1) NMDA receptors (1) NR2C subunits (1) Parasympathetic component (1) Synapse (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2005 (2) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Electrophysiological evidence for the presence of NR2C subunits of N-methyl-D-aspartate receptors in rat neurons of the nucleus tractus solitarius BJMBR Baptista,V.; Ogawa,W.N.; Aguiar,J.F.; Varanda,W.A.. The nucleus tractus solitarius (NTS) plays an important role in the control of autonomic reflex functions. Glutamate, acting on N-methyl-D-aspartate (NMDA) and non-NMDA ionotropic receptors, is the major neurotransmitter in this nucleus, and the relative contribution of each receptor to signal transmission is unclear. We have examined NMDA excitatory postsynaptic currents (NMDA-EPSCs) in the subpostremal NTS using the whole cell patch clamp technique on a transverse brainstem slice preparation. The NMDA-EPSCs were evoked by stimulation of the solitary tract over a range of membrane potentials. The NMDA-EPSCs, isolated pharmacologically, presented the characteristic outward rectification and were completely blocked by 50 µM DL-2-amino-5-phosphonopentanoic... Tipo: Info:eu-repo/semantics/other Palavras-chave: Nucleus tractus solitarius; Electrophysiology; Synapse; NMDA receptors; NR2C subunits. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000100016 The bradycardic and hypotensive responses to serotonin are reduced by activation of GABA A receptors in the nucleus tractus solitarius of awake rats BJMBR Callera,J.C.; Colombari,E.; De Luca Jr.,L.A.; Menani,J.V.. We investigated the effects of bilateral injections of the GABA receptor agonists muscimol (GABA A) and baclofen (GABA B) into the nucleus tractus solitarius (NTS) on the bradycardia and hypotension induced by iv serotonin injections (5-HT, 2 µg/rat) in awake male Holtzman rats. 5-HT was injected in rats with stainless steel cannulas implanted bilaterally in the NTS, before and 5, 15, and 60 min after bilateral injections of muscimol or baclofen into the NTS. The responses to 5-HT were tested before and after the injection of atropine methyl bromide. Muscimol (50 pmol/50 nl, N = 8) into the NTS increased basal mean arterial pressure (MAP) from 115 ± 4 to 144 ± 6 mmHg, did not change basal heart rate (HR) and reduced the bradycardia (-40 ± 14 and -73 ± 26... Tipo: Info:eu-repo/semantics/article Palavras-chave: Muscimol; GABA receptors; Nucleus tractus solitarius; Parasympathetic component; Bezold-Jarisch reflex; Awake rats. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700016 Registros recuperados: 2 Primeira ... 1 ... Última

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