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Evaluation of antimicrobial activity and cell viability of Aloe vera sponges Electron. J. Biotechnol.
Gontijo,Sávio Morato de Lacerda; Gomes,Alinne Damásia Martins; Gala-García,Alfonso; Sinisterra,Rubén Dario; Cortés,Maria Esperanza.
Background: Aloe vera L., member of the Liliaceae family, has been shown to stimulate cell proliferation and contribute to healing and angiogenesis, has anti-bacterial, anti-fungal and anti-inflammatory activity. In addition, Aloe vera can be used as a support for drug transport. Our objective is to evaluate antimicrobial activity and cytotoxicity of sponges of Aloe vera L. for use as a carrying support of drugs. Results: In this work, sponge of free Aloe vera (AV) loaded with amoxicillin (AMX) or nystatin (NYS) at 1% w/w, were prepared and physico-chemically characterized via X-ray diffraction, Fourier Transform Infrared Spectroscopy and thermal analysis. Antimicrobial potency of AV sponge alone, loaded with AMX or NYS, against strains of Streptococcus...
Tipo: Journal article Palavras-chave: Amoxicillin; Cytotoxicity; Drug transport; Nystatin.
Ano: 2013 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582013000100002
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In Vitro Assessment of Antileishmanial Activity of Natamycin and Nystatin BABT
Sidana,Arushdeep; Negi,Ajeet Kumar; Farooq,Umar.
ABSTRACT The present study was aimed to evaluate the in vitro antileishmanial activity of four different concentrations of natamycin and nystatin by using MTT 3-(4.5-dimethylthiazol-2-yl)-2.5-diphenyl tetrazolium bromide reduction assay. In vitro antileishmanial activity revealed that the IC50 of natamycin (80.49 μg/ml) and nystatin (105.7 μg/ml) was less than that of sodium stibogluconate (127.9 μg/ml), and more than amphotericin B (18.91 μg/ml).
Tipo: Info:eu-repo/semantics/article Palavras-chave: Leishmaniasis; Leishmania donovani; Antileishmanial; Natamycin; Nystatin.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100301
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