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	Provedor de dados BJPS (1) Autor Basavaiah,Kanakapura (1) Rajendraprasad,Nagaraju (1) Palavra-chave Olanzapine/determination (1) Permanganate (1) Pharmaceuticals (1) Spectrophotometry (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2009 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Determination of olanzapine by spectrophotometry using permanganate BJPS Rajendraprasad,Nagaraju; Basavaiah,Kanakapura. Two new spectrophotometric methods using permanganate as the oxidimetric reagent for the determination of olanzapine (OLP) were developed and validated as per the current ICH guidelines. The methods involved the addition of known excess of permanganate to OLP in either acid or alkaline medium followed by the determination of unreacted permanganate at 550 nm (method A) or bluish-green color of manganate at 610 nm (method B). The decrease in absorbance in method A or increase in absorbance in method B as a function of concentration of OLP was measured and related to OLP concentration. Under optimized conditions, Beer's law was obeyed over the ranges 2.0 to 20 and 1.0 to 10 μg mL-1 in method A and method B, respectively. The calculated molar absorptivity... Tipo: Info:eu-repo/semantics/article Palavras-chave: Olanzapine/determination; Spectrophotometry; Permanganate; Pharmaceuticals. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000300020 Registros recuperados: 1 Primeira ... 1 ... Última

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