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| Gayoso,Carla Wanderley; Lima,Edeltrudes de Oliveira; Souza,Evandro Leite de; Cechinel Filho,Valdir; Trajano,Vinícius Nogueira; Pereira,Fillipe de Oliveira; Lima,Igara Oliveira. |
| This study aimed to analyze the effectiveness of maleimides as inhibitors on the growth of fungal strains isolated from onychomycosis by the solid medium diffusion procedure. The results showed a promising antifungical activity of the assayed maleimides with formation of fungal growth inhibition halos oscillating between diameter 10 and 23mm. MIC was 100µg/mL for 3,4-dichloro-N-phenyl-methyl-maleimide and 3,4-dichloro-N-phenyl-propil-maleimide and 200µg/mL for 3,4-dichloro-N-phenyl-maleimide, 3,4-dichloro-N-phenyl-ethyl-maleimide and 3,4-dichloro-N-phenyl-buthyl-maleimide. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Onychomycosis; Fungi; Maleimides; Antifungical activity. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000500016 |
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| Meireles,Tereza Elizabeth Fernandes; Rocha,Marcos Fábio Gadelha; Brilhante,Raimunda Sâmia Nogueira; Cordeiro,Rossana de Aguiar; Sidrim,José Júlio Costa. |
| Onychomycosis is a fungal infection of nails caused by dermatophytes, yeasts and moulds, accounting for about 50% of onychopathies. A high frequency of onychomycosis caused by Candida species has been reported during the last few years in northeast Brazil, as well as in other regions of the world. A clinical diagnosis of onychomycosis needs to be confirmed through laboratory exams. We evaluated the importance of serial repetition of direct microscopic exams and fungal culture for the diagnosis of onychomycosis in the city of Fortaleza, Ceará, in northeast Brazil. We first made a retrospective study of 127 patients with onychomycosis, identifying the fungi that had been isolated from fingernails and toenails. We then made a prospective study of 120... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Diagnosis; Onychomycosis; Candida; Moulds and dermatophytes. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000400016 |
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| Martínez,Erick; Ameen,Mahreen; Tejada,Diana; Arenas,Roberto. |
| BACKGROUND:Dermatophytes are the main causative agent of all onychomycosis, but genus Microsporum is infrequent and the risk of acquiring the infection is often associated with exposure to risk factors.OBJECTIVES:To describe clinical characteristics of onychomycosis due to Microsporum onychomycosis in an urban population.METHODS:This was a retrospective analysis of the epidemiological and clinical features of 18Microsporum onychomycosis cases of a total of 4220 of onychomycosis cases diagnosed between May 2008 and September 2011 at the tertiary referral center for mycology in Guatemala.RESULTS:Eighteen cases of Microsporum onychomycosis (M. canis, n=10; M. gypseum, n=7; M. nanum, n=1) were identified (prevalence=0.43%). Infection was limited to nails only... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Onychomycosis; Dermatophytes; Microsporum. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000200181 |
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| Ribeiro,Clarissa Santos de Carvalho; Zaitz,Clarisse; Framil,Valéria Maria de Souza; Ottoboni,Thaíssa Santos de Carvalho; Tonoli,Melissa Santos de Carvalho; Ribeiro,Renata Pinto. |
| Onychomychosis, a nail fungus infection is the most frequent nail ailment, constituting about half of all nail disorders. It can be caused by dermatophytes, non-dermatophytes, yeasts and Prothoteca spp. Methods include 5407 samples of patients with suspected onychomycosis, studied from January 2002 to December 2006, by direct mycological examination and fungi culture. The diagnosis of onychomycosis was confirmed in samples from 3822 direct mycological and/or culture positive. The diagnosis was established by culture for fungi. Among the 1.428 identified agents, the dermatophytes were responsible for 68.6% (N = 980) of cases, followed by yeasts with 27.6% (N = 394), non-dermatophytes fungi with 2.2% (N = 31), Prothoteca spp with 0.1% (N = 2), and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Onychomycosis; Dermatophytes; Yeasts; Non-dermatophytes fungi; Prothoteca spp. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000200485 |
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| Caneschi,César Augusto; Almeida,Angelina Maria de; Martins,Francislene Juliana; Hyaric,Mireille Le; Oliveira,Manoel Marques Evangelista; Macedo,Gilson Costa; Almeida,Mauro Vieira de; Raposo,Nádia Rezende Barbosa. |
| Abstract Onychomycosis is a fungal infection of the nail caused by high densities of filamentous fungi and yeasts. Treatment for this illness is long-term, and recurrences are frequently detected. This study evaluated in vitro antifungal activities of 12 organic compounds derived from amino alcohols against standard fungal strains, such as Trichophyton rubrum CCT 5507 URM 1666, Trichophyton mentagrophytes ATCC 11481, and Candida albicans ATCC 10231. The antifungal compounds were synthesized from p-hydroxybenzaldehyde (4a-4f) and p-hydroxybenzoic acid (9a-9f). Minimum inhibitory concentrations and minimum fungicidal concentrations were determined according to Clinical and Laboratory Standards Institute protocols M38-A2, M27-A3, and M27-S4. The amine series... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amino alcohols; Amides; Lipophilicity; Antifungal activity; Onychomycosis. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000300476 |
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