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| Alves,Luciane Martins; Soares,Rodrigo Martins; Cortez,Adriana; Richtzenhain,Leonardo José; Ito,Fumio Nonma. |
| Hamsters orally inoculated with ERA and PV strains of rabies virus were sacrificed at 24, 48, 72 hours, 21 and 30 days after inoculation. Brain fragments were examined by Fluorescent Antibody test (FAT) and heminested PCR (hn-PCR). Fragments from stomach, blood, heart, and lung were examined only by hn-PCR. Sera of other hamsters, similarly inoculated, obtained at 30th day after inoculation were submitted to mouse neutralization test. The hamsters were challenged intracerebrally with CVS strain with 10(2.7)mouse LD50/0.03mL, 45 days after inoculation. Brains examined by FAT were negative. The hn-PCR detected the presence of rabies virus RNA in the lung of one animal inoculated with ERA, and in the brain, stomach, blood, and lung of PV-infected animals. The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabies; Oral administration; ERA and PV strains; Hn-PCR; Hamster. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95962003000100010 |
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| SASAKI, Naoki; LEE, Inhyung; AYUKAWA, Yu; YAMADA, Haruo; 佐々木, 直樹. |
| The effects of mosapride, a 5-hydroxytryptamine 4 (5-HT4) receptor agonist, on the motility of horse small intestine were examined by means of electrointestinography (EIG). Six adult healthy thoroughbreds were used, in which EIG signals from the small intestine were measured by a Degetorappar EGG system. Mosapride, dissolved in 200 ml water, was orally administered at a dose of 2 mg/kg. The total power of EIG signals at a frequency band of 3 cpm was 419.1 ± 122.0 (μV) 2 × cpm (n=6) before, and 2,093.6 ± 850.0 (μV)2 × cpm (n=6) after the drug administration, the latter mean value being significantly greater than the former. This result suggests that mosapride has a prokinetic action on the motility of horse small intestine. |
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Palavras-chave: Equine; Gastrokinetic agent; Mosapride; Oral administration; 5-HT4 receptor agonist. |
| Ano: 2004 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/3100 |
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| Arranz,S.E.; Sciara,A. A.; Botta,P.; Cerutti,P.; Tobin,M.; Somoza,G.M.. |
| Using biotechnology to increase the growth rates of fish is likely to reduce production costs per unit of food. Among vertebrates, fish appear to occupy a unique position, when growth patterns are considered. With few exceptions, fish species tend to grow indeterminately, implying that size is never fixed. Both hyperplasia and hypertrophy contribute to post-larval muscle growth in fish. Growth hormone (GH) - Insulin-like Growth Factor I (IGF-I) is the most important growth axis in fish. Our experimental model, the pejerrey, Odontesthes bonariensis (Ateriniformes) is a South American inland water fish considered to be a promising species for intensive aquaculture. However, one major drawback to achieve this goal is its slow growth in captivity. In order to... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Growth; Growth hormone; Muscle hypertrophy; Oral administration; Recombinant protein. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982008001300001 |
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