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| GONÇALVES,REGIANE; AYRES,VANESSA F.S.; CARVALHO,CARLOS E.; SOUZA,MARIA G.M.; GUIMARÃES,ANDERSON C.; CORRÊA,GEONE M.; MARTINS,CARLOS H.G.; TAKEARA,RENATA; SILVA,ELIANE O.; CROTTI,ANTÔNIO E.M.. |
| ABSTRACT Abnormal multiplication of oral bacteria causes dental caries and dental plaque. These diseases continue to be major public health concerns worldwide, mainly in developing countries. In this study, the chemical composition and antimicrobial activity of the essential oil of Vitex agnus-castus leaves (VAC‒EO) collected in the North of Brazil against a representative panel of cariogenic bacteria were investigated. The antimicrobial activity of VAC-EO was evaluated in terms of its minimum inhibitory concentration (MIC) values by using the broth microdilution method in 96-well microplates. The chemical constituents of VAC-EO were identified by gas chromatography (GC‒FID) and gas chromatography‒mass spectrometry (GC‒MS). VAC‒EO displayed some activity... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Streptococcus mutans; 1-8-cineole; Cariogenic bacteria; Oral pathogens. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000602825 |
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| LEMES,RAIANE S.; ALVES,CASSIA C.F.; ESTEVAM,ELISÂNGELA B.B.; SANTIAGO,MARIANA B.; MARTINS,CARLOS H.G.; SANTOS,TAINÁ C.L. DOS; CROTTI,ANTÔNIO E.M.; MIRANDA,MAYKER L.D.. |
| ABSTRACT Tooth decay is a major public health problem which affects a large number of people in several countries. Even though more than 700 bacterial species have been detected in the oral cavity, Streptococcus and Lactobacillus stand out as the genera that cause tooth decay and other periodontal diseases. In this study, essential oils from Citrus aurantifolia leaves (CL-EO) and fruit peel (CP-EO) were obtained by hydrodistillation by a Clevenger-type apparatus whereas their chemical composition was analyzed by gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Limonene (77.5 %), linalool (20.1 %), citronellal (14.5 %) and citronellol (14.2 %) were the main constituents found in the essential oils from... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Citrus aurantifolia; Limonene; Cariogenic bacteria; Essential oils; Oral pathogens. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000401285 |
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| Leandro,Luís F.; Mendes,Carlos A.; Casemiro,Luciana A.; Vinholis,Adriana H.C.; Cunha,Wilson R.; Almeida,Rosana de; Martins,Carlos H.G.. |
| In this work, we used the Minimum Inhibitory Concentration (MIC) technique to evaluate the antibacterial potential of the apitoxin produced by Apis mellifera bees against the causative agents of tooth decay. Apitoxin was assayed in naturaand in the commercially available form. The antibacterial actions of the main components of this apitoxin, phospholipase A2, and melittin were also assessed, alone and in combination. The following bacteria were tested: Streptococcus salivarius, S. sobrinus, S. mutans, S. mitis, S. sanguinis, Lactobacillus casei, and Enterococcus faecalis. The MIC results obtained for the commercially available apitoxin and for the apitoxin in natura were close and lay between 20 and 40µg / mL, which indicated good antibacterial activity.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antibacterial activity; Apitoxin; Melittin; Phospholipase A2; Tooth decay; Oral pathogens. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100147 |
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| Botelho,M.A.; Nogueira,N.A.P.; Bastos,G.M.; Fonseca,S.G.C.; Lemos,T.L.G.; Matos,F.J.A.; Montenegro,D.; Heukelbach,J.; Rao,V.S.; Brito,G.A.C.. |
| Dental caries and periodontal disease are associated with oral pathogens. Several plant derivatives have been evaluated with respect to their antimicrobial effects against such pathogenic microorganisms. Lippia sidoides Cham (Verbenaceae), popularly known as "Alecrim-pimenta" is a typical shrub commonly found in the Northeast of Brazil. Many plant species belonging to the genus Lippia yield very fragrant essential oils of potential economic value which are used by the industry for the commercial production of perfumes, creams, lotions, and deodorants. Since the leaves of L. sidoides are also extensively used in popular medicine for the treatment of skin wounds and cuts, the objective of the present study was to evaluate the composition and antimicrobial... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Lippia sidoides; Essential oil; Antimicrobial activity; Oral pathogens. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000300010 |
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| Melo,Nathalya Isabel de; Carvalho,Carlos Eduardo de; Fracarolli,Letícia; Cunha,Wilson Roberto; Veneziani,Rodrigo Cassio Sola; Martins,Carlos Henrique Gomes; Crotti,Antônio Eduardo Miller. |
| In Brazilian folk medicine, Tetradenia riparia (Hochst.) Codd. (Lamiaceae) is used to treat toothaches and dental abscesses and diseases induced by worms, bacteria, or fungi. This paper aims to investigate the chemical composition and the antibacterial effects of the essential oil obtained from Tetradenia riparia leaves (TR-EO) grown in Southeastern Brazil against a representative panel of oral pathogens. We evaluated the antibacterial activity of TR-EO in terms of the minimal inhibitory concentration (MIC). We identified aromadendrene oxide (14.0%), (E,E)-farnesol (13.6%), dronabinol (12.5%), and fenchone (6.2%) as the major constituents of TR-EO. TR-EO displayed MIC values between 31.2 and 500 μg/mL, with the lowest MIC value being obtained against... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Streptococcus mutans; Oral pathogens; Cariogenic bacteria. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000200519 |
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| Severino,Vanessa Gisele Pasqualotto; Silva,Maria Fátima das Graças Fernandes da; Lucarini,Rodrigo; Montanari,Lilian Bueno; Cunha,Wilson Roberto; Vinholis,Adriana Helena Chicharo; Martins,Carlos Henrique Gomes. |
| Extracts from Hortia oreadica afforded four dihydrocinnamic acid derivatives, isolated from the n-hexane extract, as well as limonoid guyanin and the furoquinoline alkaloid dictamnine, both isolated from the dichloromethane extract. The extracts and the isolated compounds were tested against some oral pathogens, so as to investigate their antibacterial activity. The results showed that the n-hexane extract and the compound dictamnine are the most active against the selected microorganisms. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hortia oreadica; Rutaceae; Antibacterial activity; MIC; Oral pathogens. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822009000300015 |
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