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	Provedor de dados BJMBR (1) Autor Bassani,J.W.M. (1) Bassani,R.A. (1) Godoy,C.M.G. (1) Palavra-chave Calcium (1) Electrical stimulation (1) Overdrive suppression (1) Ryanodine (1) Sarcoplasmic reticulum (1) Sinus node recovery time (1) Mais... Tipo do documento Info:eu-repo/semantics/other (1) Ano 1999 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Effect of ryanodine on sinus node recovery time determined in vitro BJMBR Bassani,J.W.M.; Godoy,C.M.G.; Bassani,R.A.. Evidence has indicated that the sarcoplasmic reticulum (SR) might be involved in the generation of spontaneous electrical activity in atrial pacemaker cells. We report the effect of disabling the SR with ryanodine (0.1 µM) on the sinus node recovery time (SNRT) measured in isolated right atria from 4-6-month-old male Wistar rats. Electrogram and isometric force were recorded at 36.5oC. Two methods for sinus node resetting were used: a) pulse: a single stimulus pulse interpolated at coupling intervals of 50, 65 or 80% of the regular spontaneous cycle length (RCL), and b) train: a 2-min train of pulses at intervals of 50, 65 or 80% of RCL. Corrected SNRT (cSNRT) was calculated as the difference between SNRT (first spontaneous cycle length after stimulation... Tipo: Info:eu-repo/semantics/other Palavras-chave: Sinus node recovery time; Overdrive suppression; Electrical stimulation; Calcium; Sarcoplasmic reticulum; Ryanodine. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000800015 Registros recuperados: 1 Primeira ... 1 ... Última

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