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	Provedor de dados BJMBR (3) Biol. Res. (1) Autor Gidlund,M. (2) Abdalla,D.S.P. (1) Ajzen,S. (1) Boschcov,P. (1) Bydlowski,Sérgio P (1) Casseb,J.S.R. (1) Duarte,A.J.S. (1) Favero,Giovani M (1) Gebara,O.C.E. (1) Levy,Débora (1) Luz,P.L. da (1) Maranhão,Raul C (1) Maria,Durvanei A (1) Moriel,P. (1) Pinto,L.B. (1) Plavnik,F.L. (1) Ronchini,K.R.O.M. (1) Rubbo,H. (1) Sevanian,A. (1) Uint,L. (1) Mais... Palavra-chave Oxidized LDL (4) 7-ketocholesterol (1) Antibodies (1) Coronary artery disease (1) Emulsion (1) Endothelin-1 (1) HIV (1) Heat shock protein (1) Hormone replacement therapy (1) Immune response (1) LDE (1) LDL (1) Lipid peroxidation (1) Lipodystrophy (1) Modified low density lipoprotein (1) Nitrate (1) Nitrotyrosine (1) Oxysterol (1) Postmenopause (1) S-nitrosothiols (1) Mais... Tipo do documento Info:eu-repo/semantics/other (2) Info:eu-repo/semantics/article (1) Journal article (1) Ano 2010 (1) 2004 (1) 2003 (1) 2002 (1) País Brazil (3) Chile (1) Idioma Inglês (4)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Synthetic nanoemulsion resembling a protein-free model of 7-ketocholesterol containing low density lipoprotein: In vitro and in vivo studies Biol. Res. Favero,Giovani M; Maranhão,Raul C; Maria,Durvanei A; Levy,Débora; Bydlowski,Sérgio P. 7-ketocholesterol (7-KC) differs from cholesterol by a functional ketone group at C7. It is an oxygenated cholesterol derivative (oxysterol), commonly present in oxidized low-density lipoprotein (LDL). Oxysterols are generated and participate in several physiologic and pathophysiologic processes. For instance, the cytotoxic effects of oxidized LDL have been widely attributed to bioactive compounds like oxysterols. The toxicity is in part due to 7-KC. Here we aimed to demonstrate the possibility of incorporating 7-KC into the synthetic nanoemulsion LDE, which resembles LDL in composition and behavior. This would provide a suitable artificial particle resembling LDL to study 7-KC metabolism. We were able to incorpórate 7-KC in several amounts into LDE. The... Tipo: Journal article Palavras-chave: Emulsion; LDL; LDE; 7-ketocholesterol; Oxidized LDL; Oxysterol. Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000400008 Cardiovascular complications and increased levels of circulating modified low density lipoprotein in HIV patients and patients with lipodystrophy BJMBR Ronchini,K.R.O.M.; Duarte,A.J.S.; Casseb,J.S.R.; Gidlund,M.. The introduction of highly active antiretroviral therapy (HAART) for patients infected with HIV has significantly prolonged the life expectancy and to some extent has restored a functional immune response. However, the premature introduction of HAART has led to a significant and alarming increase in cardiovascular complications, including myocardial infarction and the appearance of abnormal distribution of body fat seen as lipodystrophy. One key element in the development of ischemic coronary artery disease is the presence of circulating and tissue-fixed modified low density lipoprotein (mLDL) that contributes to the initiation and progression of arterial lesions and to the formation of foam cells. Even though not completely elucidated, the most likely... Tipo: Info:eu-repo/semantics/other Palavras-chave: HIV; Oxidized LDL; Modified low density lipoprotein; Lipodystrophy; Coronary artery disease. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000100016 Nitric oxide, cholesterol oxides and endothelium-dependent vasodilation in plasma of patients with essential hypertension BJMBR Moriel,P.; Sevanian,A.; Ajzen,S.; Zanella,M.T.; Plavnik,F.L.; Rubbo,H.; Abdalla,D.S.P.. The objective of the present study was to identify disturbances of nitric oxide radical (·NO) metabolism and the formation of cholesterol oxidation products in human essential hypertension. The concentrations of·NO derivatives (nitrite, nitrate, S-nitrosothiols and nitrotyrosine), water and lipid-soluble antioxidants and cholesterol oxides were measured in plasma of 11 patients with mild essential hypertension (H: 57.8 ± 9.7 years; blood pressure, 148.3 ± 24.8/90.8 ± 10.2 mmHg) and in 11 healthy subjects (N: 48.4 ± 7.0 years; blood pressure, 119.4 ± 9.4/75.0 ± 8.0 mmHg).Nitrite, nitrate and S-nitrosothiols were measured by chemiluminescence and nitrotyrosine was determined by ELISA. Antioxidants were determined by reverse-phase HPLC and cholesterol oxides... Tipo: Info:eu-repo/semantics/article Palavras-chave: Nitrotyrosine; S-nitrosothiols; Nitrate; Oxidized LDL; Lipid peroxidation; Endothelin-1. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001100007 Hormone replacement therapy increases levels of antibodies against heat shock protein 65 and certain species of oxidized low density lipoprotein BJMBR Uint,L.; Gebara,O.C.E.; Pinto,L.B.; Wajngarten,M.; Boschcov,P.; Luz,P.L. da; Gidlund,M.. Hormone replacement therapy (HRT) reduces cardiovascular risks, although the initiation of therapy may be associated with transient adverse ischemic and thrombotic events. Antibodies against heat shock protein (Hsp) and oxidized low density lipoprotein (LDL) have been found in atherosclerotic lesions and plasma of patients with coronary artery disease and may play an important role in the pathogenesis of atherosclerosis. The aim of the present study was to assess the effects of HRT on the immune response by measuring plasma levels of antibodies against Hsp 65 and LDL with a low and high degree of copper-mediated oxidative modification of 20 postmenopausal women before and 90 days after receiving orally 0.625 mg equine conjugate estrogen plus 2.5 mg... Tipo: Info:eu-repo/semantics/other Palavras-chave: Hormone replacement therapy; Postmenopause; Oxidized LDL; Heat shock protein; Immune response; Antibodies. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000400011 Registros recuperados: 4 Primeira ... 1 ... Última

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