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| Shabana,; Hasnain,Shahida. |
| BACKGROUND: Obesity is a complex disorder and has been increasing globally at alarming rates including Pakistan. However, there is scarce research on understanding obesity genetics in Pakistan. Leptin is a hormone secreted by adipocytes in response to satiety and correlates with body weight. Any mutations in the LEP gene have an adverse effect on energy regulation pathway and lead to severe, early onset obesity. To date, only eight mutations have been described in the LEP gene of which p. N103K is one. METHODS: We aimed to analyze the prevalence of this mutation in Pakistani subjects. A total of 475 subjects were genotyped by PCR-RFLP analysis and their serum profiling was done. RESULTS: Results showed that this mutation was present only in one male child... |
| Tipo: Journal article |
Palavras-chave: Obesity; Leptin; P. N103K; Pakistan. |
| Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100023 |
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| Zia-Ul-Haq,Muhammad; Ahmad,Shakeel; Bukhari,Shazia Anwer; Amarowicz,Ryszard; Ercisli,Sezai; Jaafar,Hawa ZE. |
| BACKGROUND: In recent years, the desire to adopt a healthy diet has drawn attention to legume seeds and food products derived from them. Mash bean is an important legume crop used in Pakistan however a systematic mapping of the chemical composition of mash bean seeds is lacking. Therefore seeds of four mash bean (Vigna mungo (L.) Hepper, family Leguminoseae) cultivars (NARC-Mash-1, NARC-Mash-2, NARC-Mash-3, NARC-Mash-97) commonly consumed in Pakistan have been analyzed for their chemical composition, antioxidant potential and biological activities like inhibition of formation of advanced glycation end products (AGE) activity and tyrosinase inhibition activity. RESULTS: The investigated cultivars varied in terms of biochemical composition to various... |
| Tipo: Journal article |
Palavras-chave: Nutrients; Antioxidant potential; Mash bean cultivar; Pakistan. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100023 |
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| Khatoon,Lubna; Baliraine,Frederick N.; Malik,Salman A.; Yan,Guiyun. |
| Plasmodium vivax and Plasmodium falciparum are becoming resistant to drugs including antifolates, sulphonamides and chloroquine. This study was focused at sequence analysis of resistant genes of these parasites against sulphadoxine-pyrimethamine and chloroquine, from Bannu, Pakistan. Known mutations were detected at codons 57, 58 and 117 of pvdhfr gene of P. vivax, while none of the isolates had any pvdhps mutation. Similarly P. falciparum isolates exhibited double 59R + 108N mutations in pfdhfr, and single 437G in pfdhps thus demonstrating the existance of triple mutant 59R + 108N + 437G haplotype in this region. The key chloroquine resistance mutation, 76T in pfcrt was observed in 100% of the P. falciparum isolates, with haplotype SVMNT which is also... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Plasmodium vivax; Plasmodium falciparum; Sequence analysis; Pakistan. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000500013 |
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| Khatoon,Lubna; Khan,Inam Ullah; Shah,Shahid Ali; Jan,Muhammad Ishtiaq; Ullah,Farhat; Malik,Salman Akbar. |
| Malaria is one of the serious diseases threatening human health in Pakistan and contributes to a large proportion of the total malaria deaths in South Asia. However, little is known about the nature and extent of genetic diversity of the malarial parasites circulating in Pakistan. This study was designed to assess the infection status of Plasmodium and the genetic diversity of Plasmodium vivax and Plasmodium falciparum by analyzing msp-3α, msp-3β and msp-1, msp-2 genes respectively using allele specific nested PCR and RFLP assays. For this purpose, 130 field isolates were collected from the individuals who exhibited clinical symptoms associated with malaria in the Kohat region of Khyber Pakhtoonkhwa (KPK), Pakistan. Among 130 blood samples collected, P.... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Plasmodium vivax; Plasmodium falciparum; Genetic variation; Pakistan. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000200014 |
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| Riaz,Saba; Bashir,Muhammad Faisal; Haider,Saleem; Rahid,Naeem. |
| Abstract The presented study had two objectives. The first was to examine distributions of Hepatitis C Virus (HCV) genotypes in Sindh, Pakistan, where HCV is prevalent. The other was to explore clinically relevant relationships between the genotypes, viral load (measured by real-time polymerase chain reaction assays) and biochemical markers. For this, 1471 HCV-infected patients in six cities in Sindh were recruited and sampled. HCV genotype distributions varied among the cities, but genotype 3a was most prevalent, followed by 3b, 1a and 1b (detected in 51.5, 22.7. 9.25 and 3.2% of the cases, respectively). No type-specific sequences were detected in serum samples from 189 (12.8%) of the 1471 patients. Frequencies of low (<200,000 IU/mL serum),... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sindh; HCV; Pakistan; Genotype; Biomarkers; Viral load. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000400980 |
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| Ali,Asad; Hussain,Adil; Ahmad,Musharaf. |
| Field survey of the cucurbit crops revealed a high incidence of Cucumber green mottle mosaic virus (CGMMV) in Khyber Pakhtunkhwa Province (KPK), Pakistan. Among the seven districts surveyed, average percent incidence of CGMMV was recorded up to 58.1% in district Nowshera, followed by 51.1% in district Charsada, 40.5% in district Swabi and 37.3% in district Mardan. In Swat and Dir districts average incidence CGMMV was recorded upto 31.2% and 29.4%, respectively. Among the different crops highest incidence in plain areas of KPK was recorded in bottle gourd (59.3%) followed by 56.3% in Squash, 54.5% in Pumpkin, 45.5% in Melon, 41.7% in Cucumber and 29.9% in Sponge gourd. In Northern hilly areas highest incidence of CGMMV (52.9%) was observed in pumpkin,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cucurbit; CGMMV; Incidence; Tobamovirus; Pakistan. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000400015 |
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| Bell, Andrew Reid; New York University, Department of Environmental Studies; andrew.reid.bell@nyu.edu; Shah, M. Azeem A.; International Water Management Institute; a.shah@cgiar.org; Anwar, Arif; International Water Management Institute; a.anwar@cgiar.org; Ringler, Claudia; International Food Policy Research Institute; c.ringler@cgiar.org. |
| The Indus Basin Irrigation System suffers significant inequity in access to surface water across its millions of users. Information, i.e., monitoring and reporting of water availability, may be of value in improving conditions across the basin, and we investigated this via an experimental game of water distribution in Punjab, Pakistan. We found evidence that flow information allowed players to take more effective action to target overuse, and that overall activities that might bring social disapproval were reduced with information. However, we did not find any overall improvement in equity across the system, suggesting that information on its own might not be sufficient to lead to better water distribution among irrigators. |
| Tipo: Peer-Reviewed Reports |
Palavras-chave: Framed field experiment; Irrigation; Pakistan. |
| Ano: 2015 |
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| Abidi-Habib, Mehjabeen; Government College University Lahore; mamie@wol.net.pk; Lawrence, Anna; Oxford University; anna.lawrence@eci.ox.ac.uk. |
| The Shimshal Nature Trust is an indigenous institution rooted in a thriving and dynamic culture that links the local ecology and society. It has deployed identity, traditional knowledge, science, and institutional innovation to adapt to outside challenges without destroying local commons management. This paper reviews scholarly debate on natural resource management and uses resilience theory to examine this complex adaptive system. Two disturbances to Shimshal resilience prompted by a national park and a new road are traced. Shimshali responses include social processes of learning, knowledge systems, and renewal. Ways in which adaptive renewal cycles involve Revolt, a short, fast reaction, and Remember, a larger, slower cascade, are put in perspective.... |
| Tipo: Peer-Reviewed article |
Palavras-chave: Pakistan; Indigenous institution; Local commons management; Ecological resilience; Complex adaptive systems; Social learning; Renewal; National park; New road; Community participation. |
| Ano: 2007 |
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| Bell, Andrew Reid; Department of Environmental Studies, New York University; ab6176@nyu.edu; Ward, Patrick S.; International Food Policy Research Institute (IFPRI), Washington, D.C.; p.ward@cgiar.org; Shah, M. Azeem Ali; International Water Management Institute (IWMI), Lahore, Pakistan; Lahore University of Management Sciences (LUMS), Pakistan; a.shah@cgiar.org. |
| Conventional wisdom in many agricultural systems across the world is that farmers cannot, will not, or should not pay the full costs associated with surface water delivery. Across Organisation for Economic Co-operation and Development (OECD) countries, only a handful can claim complete recovery of operation, maintenance, and capital costs; across Central and South Asia, fees are lower still, with farmers in Nepal, India, and Kazakhstan paying fractions of a U.S. penny for a cubic meter of water. In Pakistan, fees amount to roughly USD 1-2 per acre per season. However, farmers in Pakistan spend orders of magnitude more for diesel fuel to pump groundwater each season, suggesting a latent willingness to spend for water that, under the right conditions, could... |
| Tipo: Peer-Reviewed Reports |
Palavras-chave: Agent-based model; Efficiency; Equity; Irrigation; Pakistan; Water. |
| Ano: 2016 |
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| Rashid,A; Khan,JA; Khan,MS; Rasheed,K; Maqbool,A; Iqbal,J. |
| A total of 310 blood smears were collected from sheep of the Livestock Experiment Station, Qadirabad, Sahiwal district, Pakistan, and surrounding areas. The samples were examined microscopically and 30 (9.67%) were positive for babesiosis. The animals were divided into two groups (A and B) for chemotherapy. Group A sheep were treated with diminazene diaceturate while group B animals received imidocarb dipropionate. Drug efficacy was determined by negative blood smear examination. Diminazene diaceturate effectiveness against babesiosis was 80% while that of imidocarb dipropionate was 100%. Hematological studies revealed a significant decrease in hemoglobin concentrations and hematocrit values for Babesia-positive animals compared to healthy controls. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Babesiosis; Sheep; Hemoglobin; Hematocrit; Diminazene; Imidocarb; Pakistan. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000400008 |
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| Shahzad, Azeem; Sarwar Khan, Muhammad; Ashraf, Kamran; Avais, Muhammad; Pervez, Khalid; Ali Khan, Jawaria. |
| The current study was conducted to find out the epidemiological status of toxoplasmosis in cats, dogs and human population in Lahore city of Pakistan and to determine the possibility of transmission of toxoplasmosis from cats and dogs to their owners. Overall 56% cats were seropositive for anti-Toxoplasma antibodies. Stray cats had the high prevalence (64%) followed by domestic cats (48%). The highest prevalence (71%) was detected in cat in the 7 year or above age group. The seropositivity percentage of toxoplasmosis was highest in local breeds of the cats (64%). Overall 39% dogs were seropositive for anti- Toxoplasma antibodies. Stray dogs had the high prevalence (50%) than the domestic dogs (28%). The highest prevalence of toxoplasmosis (45.9%) was... |
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Palavras-chave: Toxoplasmosis; Prevalence; Dogs; Cats; Pakistan. |
| Ano: 2006 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/998 |
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| Shah,A; Rahim,S; Bhatti,KH; Khan,A; Din,N; Imran,M; Mohsin,M; Ishtiaq,M; Nabila,A; Ansari,A; Hussain,S; Zafar,M; Mushtaq,M; Mumtaz,E; Iqbal,J. |
| Sargodha district is one of the least studied regions of Pakistan regarding its ethnobotanical values. This paper is the frst report related to the documentation and conservation status of the tree species in the Sargodha district, and their folk ethnobotanical uses. An interview base survey was conducted in the study area in 2010-2013. The ethnobotanical data revealed the use of 100 tree species (6 gymnosperms, 94 angiosperms) belonging to 77 genera (6 gymnosperms, 71 angiosperms) and 39 families (4 gymnosperms, 35 angiosperms), with the Fabaceae ranking first with 19 tree species, followed by the Moraceae (12 species). Tree species like Aegle marmelos, Butea monosperma, Diospyrus malabarica, Gmelina arborea, Kigelia africana, Manilkara hexandra,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ethnobotanical study; Medicinal plants; Sargodha; Pakistan. |
| Ano: 2015 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-56572015000100006 |
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| Abbas, Faisal; Hiemenz, Ulrich. |
| This study describes the macroeconomic determinants of health care spending in a broad context using time series data from Pakistan on economic, demographic, social, and political variables. The data spans a period from 1972- 2006 and was analyzed using cointegration and error correction approaches. All variables were found to be first difference stationary and the results confirm the presence of one cointegrating vector. This proves the existence of a long-run relationship between public health care expenditures and the other variables used in the model. The income elasticity of public health care expenditures is estimated at 0.23. As this value is less than unity it suggests that, contrary to most of the Organization for Economic Co-operation and... |
| Tipo: Working Paper |
Palavras-chave: Public Health Expenditures; Unemployment; Urbanization; Cointegration; Time series; Pakistan; Health Economics and Policy. |
| Ano: 2011 |
URL: http://purl.umn.edu/118422 |
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| Registros recuperados: 40 | |
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