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| Jacquemot, Loic; Bettarel, Yvan; Monjol, Joanne; Corre, Erwan; Halary, Sebastien; Desnues, Christelle; Bouvier, Thierry; Ferrier-pages, Christine; Baudoux, Anne-claire. |
| Biological control using bacteriophages is a promising approach for mitigating the devastating effects of coral diseases. Several phages that infect Vibrio coralliilyticus, a widespread coral pathogen, have been isolated, suggesting that this bacterium is permissive to viral infection and is, therefore, a suitable candidate for treatment by phage therapy. In this study, we combined functional and genomic approaches to evaluate the therapeutic potential of BONAISHI, a novel V. coralliilyticus phage, which was isolated from the coral reef in Van Phong Bay (Vietnam). BONAISHI appears to be strictly lytic for several pathogenic strains of V. coralliilyticus and remains infectious over a broad range of environmental conditions. This candidate has an unusually... |
| Tipo: Text |
Palavras-chave: Phage therapy; Coral disease; Vibrio coralliilyticus; Viral genomics; Phage-host interactions. |
| Ano: 2018 |
URL: https://archimer.ifremer.fr/doc/00465/57717/74946.pdf |
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