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Comparison of the sedative effects of morphine, meperidine or fentanyl, in combination with acepromazine, in dogs Ciência Rural
Gomes,Viviane Horta; Monteiro,Eduardo Raposo; Dias,Raquel Sartori; Oliveira,Renato Leão Sá de; Silva,Marta Fernanda Albuquerque da; Coelho,Karina.
This study aimed to compare the sedative effects of morphine, meperidine and fentanyl, in combination with acepromazine (ACP) and their effects on physiologic values in dogs. Six healthy beagle dogs were randomly assigned to four treatments with 7-day washout intervals. In three treatments, ACP (0.05mg kg-1) was administered and 20 minutes later, the dogs received administration of 0.5mg kg-1 of morphine (ACPMOR), 5mg kg-1 of meperidine (ACPMEP) or 5µg kg-1 of fentanyl (ACPFEN). In treatment ACP HD MOR, 0.1mg kg-1 of ACP was administered in combination with 0.5mg kg-1 of morphine. All drugs were administered intravenously. Sedation scores were evaluated by a numeric descriptive scale (NDS: 0-3) and a simple numeric scale (SNS: 0-10). All variables were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sedation; Opioids; Phenothiazines.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782011000800018
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Influence of acepromazine on the cardiovascular actions of dobutamine in isoflurane-anesthetized horses Ciência Rural
Monteiro,Eduardo Raposo; Souza,Juliano Ferreira Fernandes de; Baiotto,Gustavo Cancian; Figueiró,Giuliano Moraes; Rangel,Julia da Penha Piccoli; Coelho,Clarisse Simões.
The influence of acepromazine (ACP) on the effectiveness of dobutamine (DBT) in increasing blood pressure during isoflurane (ISO) anesthesia was evaluated in six horses. On separate occasions, the horses were randomly assigned to receive NaCl 0.9% (Control), ACP 0.025mg kg-1 and ACP 0.05mg kg-1. The experimental treatment was administered prior to induction of anesthesia. Maintenance of anesthesia was performed under conditions of normocapnia with ISO in oxygen. Dobutamine was administered at progressively increasing infusion rates until mean arterial pressure (MAP) reached 70mmHg or until a maximum infusion rate of 5.0µg kg-1 min-1. Compared with baseline, DBT increased heart rate, systolic, diastolic and mean blood pressures in all treatments. However,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Phenothiazines; Catecholamines; Equine; Inhalational anesthesia.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782011000300017
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